F-18 FDG-PET-CT in the Diagnostic of a Late Medullary Thyroid Carcinoma Recurrence in a Patient with Follicular-Papillary Thyroid Cancer

Mixed medullary and follicular or papillary carcinoma of thyroid is an extremely rare tumor, characterized by coexistence of morphological and immunohistochemical features of both medullary carcinoma and follicular (or papillary) carcinoma. This case report describes for the first time in the index...

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Main Authors: Doina Piciu, Andra Piciu
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2014/741262
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author Doina Piciu
Andra Piciu
author_facet Doina Piciu
Andra Piciu
author_sort Doina Piciu
collection DOAJ
description Mixed medullary and follicular or papillary carcinoma of thyroid is an extremely rare tumor, characterized by coexistence of morphological and immunohistochemical features of both medullary carcinoma and follicular (or papillary) carcinoma. This case report describes for the first time in the indexed database a late recurrence of a medullary thyroid carcinoma initially diagnosed as follicular-papillary form, treated and monitored accordingly. After 14 years, a superior mediastinum tumor was discovered incidentally at a thorax computer tomography. The whole-body I-131 scan was negative and F-18 FDG-PET-CT showed glucose avidity of the tumor. The patient was operated on and the histology revealed medullary thyroid carcinoma. If there are no possibilities to have routinely extensive immunohistologic profiles, it is recommended to check the serum calcitonin, at least in any patient with confirmed thyroid carcinoma.
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spelling doaj-art-bdb3d7ca3fda45b2b25df65691d2be372025-02-03T01:22:24ZengWileyCase Reports in Endocrinology2090-65012090-651X2014-01-01201410.1155/2014/741262741262F-18 FDG-PET-CT in the Diagnostic of a Late Medullary Thyroid Carcinoma Recurrence in a Patient with Follicular-Papillary Thyroid CancerDoina Piciu0Andra Piciu1Department of Nuclear Medicine, “Ion Chiricuţă” Institute of Oncology, 34-36 Republicii Street, 400015 Cluj-Napoca, RomaniaFaculty of Medicine, “Iuliu Haţieganu” University of Medicine and Pharmacy, 6-8 V. Babes Street, 400012 Cluj-Napoca, RomaniaMixed medullary and follicular or papillary carcinoma of thyroid is an extremely rare tumor, characterized by coexistence of morphological and immunohistochemical features of both medullary carcinoma and follicular (or papillary) carcinoma. This case report describes for the first time in the indexed database a late recurrence of a medullary thyroid carcinoma initially diagnosed as follicular-papillary form, treated and monitored accordingly. After 14 years, a superior mediastinum tumor was discovered incidentally at a thorax computer tomography. The whole-body I-131 scan was negative and F-18 FDG-PET-CT showed glucose avidity of the tumor. The patient was operated on and the histology revealed medullary thyroid carcinoma. If there are no possibilities to have routinely extensive immunohistologic profiles, it is recommended to check the serum calcitonin, at least in any patient with confirmed thyroid carcinoma.http://dx.doi.org/10.1155/2014/741262
spellingShingle Doina Piciu
Andra Piciu
F-18 FDG-PET-CT in the Diagnostic of a Late Medullary Thyroid Carcinoma Recurrence in a Patient with Follicular-Papillary Thyroid Cancer
Case Reports in Endocrinology
title F-18 FDG-PET-CT in the Diagnostic of a Late Medullary Thyroid Carcinoma Recurrence in a Patient with Follicular-Papillary Thyroid Cancer
title_full F-18 FDG-PET-CT in the Diagnostic of a Late Medullary Thyroid Carcinoma Recurrence in a Patient with Follicular-Papillary Thyroid Cancer
title_fullStr F-18 FDG-PET-CT in the Diagnostic of a Late Medullary Thyroid Carcinoma Recurrence in a Patient with Follicular-Papillary Thyroid Cancer
title_full_unstemmed F-18 FDG-PET-CT in the Diagnostic of a Late Medullary Thyroid Carcinoma Recurrence in a Patient with Follicular-Papillary Thyroid Cancer
title_short F-18 FDG-PET-CT in the Diagnostic of a Late Medullary Thyroid Carcinoma Recurrence in a Patient with Follicular-Papillary Thyroid Cancer
title_sort f 18 fdg pet ct in the diagnostic of a late medullary thyroid carcinoma recurrence in a patient with follicular papillary thyroid cancer
url http://dx.doi.org/10.1155/2014/741262
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