Pulmonary Nocardiosis: Review of Cases and an Update
Nocardia, a branching, filamentous bacteria, is widely distributed in the environment and can cause human infection in immune-compromised hosts. Inhalation of Nocardia leads to pulmonary disease. Microbiology laboratory processed the clinical samples from patients with respiratory infections. Smears...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/2016/7494202 |
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| author | Malini Shariff Jayanthi Gunasekaran |
| author_facet | Malini Shariff Jayanthi Gunasekaran |
| author_sort | Malini Shariff |
| collection | DOAJ |
| description | Nocardia, a branching, filamentous bacteria, is widely distributed in the environment and can cause human infection in immune-compromised hosts. Inhalation of Nocardia leads to pulmonary disease. Microbiology laboratory processed the clinical samples from patients with respiratory infections. Smears were prepared from the samples and were stained and cultured. Five cases were positive for Nocardia. They were treated with the trimethoprim-sulfamethoxazole combination. The disease was cured in three patients, and two died due to other comorbid conditions leading to complications. Nocardiosis is encountered in parts of the world even where it is not endemic due to increased world travel. So physicians and laboratory staff should be aware of this and try to diagnose it. Early detection can lead to the prompt initiation of treatment and reduced mortality in these patients. Patients with disseminated or severe nocardiosis should be treated with combination therapy with two or more active agents. |
| format | Article |
| id | doaj-art-bd9805984e7543a8ad592666333d49ef |
| institution | Kabale University |
| issn | 1198-2241 1916-7245 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Respiratory Journal |
| spelling | doaj-art-bd9805984e7543a8ad592666333d49ef2025-02-03T01:28:13ZengWileyCanadian Respiratory Journal1198-22411916-72452016-01-01201610.1155/2016/74942027494202Pulmonary Nocardiosis: Review of Cases and an UpdateMalini Shariff0Jayanthi Gunasekaran1Department of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi 110007, IndiaDepartment of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi 110007, IndiaNocardia, a branching, filamentous bacteria, is widely distributed in the environment and can cause human infection in immune-compromised hosts. Inhalation of Nocardia leads to pulmonary disease. Microbiology laboratory processed the clinical samples from patients with respiratory infections. Smears were prepared from the samples and were stained and cultured. Five cases were positive for Nocardia. They were treated with the trimethoprim-sulfamethoxazole combination. The disease was cured in three patients, and two died due to other comorbid conditions leading to complications. Nocardiosis is encountered in parts of the world even where it is not endemic due to increased world travel. So physicians and laboratory staff should be aware of this and try to diagnose it. Early detection can lead to the prompt initiation of treatment and reduced mortality in these patients. Patients with disseminated or severe nocardiosis should be treated with combination therapy with two or more active agents.http://dx.doi.org/10.1155/2016/7494202 |
| spellingShingle | Malini Shariff Jayanthi Gunasekaran Pulmonary Nocardiosis: Review of Cases and an Update Canadian Respiratory Journal |
| title | Pulmonary Nocardiosis: Review of Cases and an Update |
| title_full | Pulmonary Nocardiosis: Review of Cases and an Update |
| title_fullStr | Pulmonary Nocardiosis: Review of Cases and an Update |
| title_full_unstemmed | Pulmonary Nocardiosis: Review of Cases and an Update |
| title_short | Pulmonary Nocardiosis: Review of Cases and an Update |
| title_sort | pulmonary nocardiosis review of cases and an update |
| url | http://dx.doi.org/10.1155/2016/7494202 |
| work_keys_str_mv | AT malinishariff pulmonarynocardiosisreviewofcasesandanupdate AT jayanthigunasekaran pulmonarynocardiosisreviewofcasesandanupdate |