Dynamics of a Viral Infection Model with General Contact Rate between Susceptible Cells and Virus Particles

This paper investigates the dynamic behavior of a viral infection model with general contact rate between susceptible host cells and free virus particles. If the basic reproduction number of the virus is less than unity, by LaSalle’s invariance principle, the disease-free equilibrium is globally asy...

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Main Authors: Chenxi Dai, Cui Ma, Lijuan Song, Kaifa Wang
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Abstract and Applied Analysis
Online Access:http://dx.doi.org/10.1155/2014/546795
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author Chenxi Dai
Cui Ma
Lijuan Song
Kaifa Wang
author_facet Chenxi Dai
Cui Ma
Lijuan Song
Kaifa Wang
author_sort Chenxi Dai
collection DOAJ
description This paper investigates the dynamic behavior of a viral infection model with general contact rate between susceptible host cells and free virus particles. If the basic reproduction number of the virus is less than unity, by LaSalle’s invariance principle, the disease-free equilibrium is globally asymptotically stable. If the basic reproduction number of the virus is greater than unity, then the virus persists in the host and the endemic equilibrium is locally asymptotically stable.
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institution Kabale University
issn 1085-3375
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language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series Abstract and Applied Analysis
spelling doaj-art-bd92e76236b44bce895132e49fbfbb282025-02-03T00:59:13ZengWileyAbstract and Applied Analysis1085-33751687-04092014-01-01201410.1155/2014/546795546795Dynamics of a Viral Infection Model with General Contact Rate between Susceptible Cells and Virus ParticlesChenxi Dai0Cui Ma1Lijuan Song2Kaifa Wang3Department of Mathematics, School of Biomedical Engineering, Third Military Medical University, Chongqing 400038, ChinaDepartment of Mathematics, School of Biomedical Engineering, Third Military Medical University, Chongqing 400038, ChinaDepartment of Mathematics, School of Biomedical Engineering, Third Military Medical University, Chongqing 400038, ChinaDepartment of Mathematics, School of Biomedical Engineering, Third Military Medical University, Chongqing 400038, ChinaThis paper investigates the dynamic behavior of a viral infection model with general contact rate between susceptible host cells and free virus particles. If the basic reproduction number of the virus is less than unity, by LaSalle’s invariance principle, the disease-free equilibrium is globally asymptotically stable. If the basic reproduction number of the virus is greater than unity, then the virus persists in the host and the endemic equilibrium is locally asymptotically stable.http://dx.doi.org/10.1155/2014/546795
spellingShingle Chenxi Dai
Cui Ma
Lijuan Song
Kaifa Wang
Dynamics of a Viral Infection Model with General Contact Rate between Susceptible Cells and Virus Particles
Abstract and Applied Analysis
title Dynamics of a Viral Infection Model with General Contact Rate between Susceptible Cells and Virus Particles
title_full Dynamics of a Viral Infection Model with General Contact Rate between Susceptible Cells and Virus Particles
title_fullStr Dynamics of a Viral Infection Model with General Contact Rate between Susceptible Cells and Virus Particles
title_full_unstemmed Dynamics of a Viral Infection Model with General Contact Rate between Susceptible Cells and Virus Particles
title_short Dynamics of a Viral Infection Model with General Contact Rate between Susceptible Cells and Virus Particles
title_sort dynamics of a viral infection model with general contact rate between susceptible cells and virus particles
url http://dx.doi.org/10.1155/2014/546795
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AT lijuansong dynamicsofaviralinfectionmodelwithgeneralcontactratebetweensusceptiblecellsandvirusparticles
AT kaifawang dynamicsofaviralinfectionmodelwithgeneralcontactratebetweensusceptiblecellsandvirusparticles