Use of “ARRIAH-AviFluVac” vaccine in turkeys, geese and ducks
“ARRIAH-AviFluVac” vaccine against H5 avian influenza was demonstrated to be effective for ducks, geese and turkeys both in the laboratory and production environment. When administered to ducks at 0.5; 1.0 and 1.5 cm3, the vaccine provided 100%-effective protection of birds against the disease and...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Da Vinci Media
2024-09-01
|
| Series: | Ветеринария сегодня |
| Subjects: | |
| Online Access: | https://veterinary.arriah.ru/jour/article/view/845 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832086680412094464 |
|---|---|
| author | N. V. Moroz S. V. Frolov V. N. Irza L. O. Scherbakova V. Yu. Kulakov |
| author_facet | N. V. Moroz S. V. Frolov V. N. Irza L. O. Scherbakova V. Yu. Kulakov |
| author_sort | N. V. Moroz |
| collection | DOAJ |
| description | “ARRIAH-AviFluVac” vaccine against H5 avian influenza was demonstrated to be effective for ducks, geese and turkeys both in the laboratory and production environment. When administered to ducks at 0.5; 1.0 and 1.5 cm3, the vaccine provided 100%-effective protection of birds against the disease and death after challenge with the relevant high pathogenicity avian influenza virus of subtype H5N1, clade 2.3.4.4b. Singular 0.5–1.5 cm3 inoculation induced formation of antibodies, which were detected in the hemagglutination inhibition test at the titres that ranged from 4.3 to 6.1 log2. The vaccine facilitated 9–26-fold decrease in the virulent virus shedding by the ducks. Protection of turkeys vaccinated at the dose of 1.0 cm3 was maintained at the level of 87.5% after challenge with high pathogenicity avian influenza virus of subtype H5N1, clade 2.3.4.4b. The vaccine induced formation of antibodies at the titres of 4.9 and 5.5 log2 in turkeys after singular and double vaccination at the dose of 1.0 cm3, respectively. It was demonstrated, that after double administration of 1.0 cm3 of “ARRIAH-AviFluVac” vaccine, the post-vaccinal avian influenza antibody level exceeded 5.0 log2 in 75.9–90.0% of the geese population. The most appropriate way of the vaccine use in turkeys, ducks and geese involves at least its double administration at the double commercial dose. Higher species resistance of ducks to the challenge with avian influenza virus of subtype H5, clade 2.3.4.4bas compared to turkeys was also demonstrated. |
| format | Article |
| id | doaj-art-bd8b8180ddcb46fa90430ef424d601f6 |
| institution | Kabale University |
| issn | 2304-196X 2658-6959 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Da Vinci Media |
| record_format | Article |
| series | Ветеринария сегодня |
| spelling | doaj-art-bd8b8180ddcb46fa90430ef424d601f62025-02-06T09:52:10ZengDa Vinci MediaВетеринария сегодня2304-196X2658-69592024-09-0113324825410.29326/2304-196X-2024-13-3-248-254680Use of “ARRIAH-AviFluVac” vaccine in turkeys, geese and ducksN. V. Moroz0S. V. Frolov1V. N. Irza2L. O. Scherbakova3V. Yu. Kulakov4Federal Centre for Animal HealthFederal Centre for Animal HealthFederal Centre for Animal HealthFederal Centre for Animal HealthFederal Centre for Animal Health“ARRIAH-AviFluVac” vaccine against H5 avian influenza was demonstrated to be effective for ducks, geese and turkeys both in the laboratory and production environment. When administered to ducks at 0.5; 1.0 and 1.5 cm3, the vaccine provided 100%-effective protection of birds against the disease and death after challenge with the relevant high pathogenicity avian influenza virus of subtype H5N1, clade 2.3.4.4b. Singular 0.5–1.5 cm3 inoculation induced formation of antibodies, which were detected in the hemagglutination inhibition test at the titres that ranged from 4.3 to 6.1 log2. The vaccine facilitated 9–26-fold decrease in the virulent virus shedding by the ducks. Protection of turkeys vaccinated at the dose of 1.0 cm3 was maintained at the level of 87.5% after challenge with high pathogenicity avian influenza virus of subtype H5N1, clade 2.3.4.4b. The vaccine induced formation of antibodies at the titres of 4.9 and 5.5 log2 in turkeys after singular and double vaccination at the dose of 1.0 cm3, respectively. It was demonstrated, that after double administration of 1.0 cm3 of “ARRIAH-AviFluVac” vaccine, the post-vaccinal avian influenza antibody level exceeded 5.0 log2 in 75.9–90.0% of the geese population. The most appropriate way of the vaccine use in turkeys, ducks and geese involves at least its double administration at the double commercial dose. Higher species resistance of ducks to the challenge with avian influenza virus of subtype H5, clade 2.3.4.4bas compared to turkeys was also demonstrated.https://veterinary.arriah.ru/jour/article/view/845high pathogenicity avian influenzah5 avian influenza virusinactivated vaccineimmunogenicityducksgeeseturkeys |
| spellingShingle | N. V. Moroz S. V. Frolov V. N. Irza L. O. Scherbakova V. Yu. Kulakov Use of “ARRIAH-AviFluVac” vaccine in turkeys, geese and ducks Ветеринария сегодня high pathogenicity avian influenza h5 avian influenza virus inactivated vaccine immunogenicity ducks geese turkeys |
| title | Use of “ARRIAH-AviFluVac” vaccine in turkeys, geese and ducks |
| title_full | Use of “ARRIAH-AviFluVac” vaccine in turkeys, geese and ducks |
| title_fullStr | Use of “ARRIAH-AviFluVac” vaccine in turkeys, geese and ducks |
| title_full_unstemmed | Use of “ARRIAH-AviFluVac” vaccine in turkeys, geese and ducks |
| title_short | Use of “ARRIAH-AviFluVac” vaccine in turkeys, geese and ducks |
| title_sort | use of arriah avifluvac vaccine in turkeys geese and ducks |
| topic | high pathogenicity avian influenza h5 avian influenza virus inactivated vaccine immunogenicity ducks geese turkeys |
| url | https://veterinary.arriah.ru/jour/article/view/845 |
| work_keys_str_mv | AT nvmoroz useofarriahavifluvacvaccineinturkeysgeeseandducks AT svfrolov useofarriahavifluvacvaccineinturkeysgeeseandducks AT vnirza useofarriahavifluvacvaccineinturkeysgeeseandducks AT loscherbakova useofarriahavifluvacvaccineinturkeysgeeseandducks AT vyukulakov useofarriahavifluvacvaccineinturkeysgeeseandducks |