Anesthetic Related Advances with Cyclodextrins
Cyclodextrins encapsulate and electrostatically bind to lipophilic molecules. The exterior of cyclodextrins are water-soluble and maintain aqueous solubility despite encapsulation of non-aqueous soluble molecules. This unique ability to encapsulate lipophilic molecules and maintain water solubility...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2007-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2007.83 |
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| _version_ | 1832552044844548096 |
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| author | Mark Welliver John P. McDonough |
| author_facet | Mark Welliver John P. McDonough |
| author_sort | Mark Welliver |
| collection | DOAJ |
| description | Cyclodextrins encapsulate and electrostatically bind to lipophilic molecules. The exterior of cyclodextrins are water-soluble and maintain aqueous solubility despite encapsulation of non-aqueous soluble molecules. This unique ability to encapsulate lipophilic molecules and maintain water solubility confers numerous pharmacologic advantages for both drug delivery and removal. Cyclodextrins, a component part of supramolecular chemistry, may be in its infancy of anesthetic application but recent advances have been described as novel and revolutionary. A review of current research coupled with an understanding of cyclodextrin properties is necessary to fully appreciate the current uses and future potentials of these unique molecules. |
| format | Article |
| id | doaj-art-bd881f9f2305449bbd5c8d64745aa8cb |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2007-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-bd881f9f2305449bbd5c8d64745aa8cb2025-02-03T05:59:52ZengWileyThe Scientific World Journal1537-744X2007-01-01736437110.1100/tsw.2007.83Anesthetic Related Advances with CyclodextrinsMark Welliver0John P. McDonough1University of North Florida, Jacksonville, FL, USAUniversity of North Florida, Jacksonville, FL, USACyclodextrins encapsulate and electrostatically bind to lipophilic molecules. The exterior of cyclodextrins are water-soluble and maintain aqueous solubility despite encapsulation of non-aqueous soluble molecules. This unique ability to encapsulate lipophilic molecules and maintain water solubility confers numerous pharmacologic advantages for both drug delivery and removal. Cyclodextrins, a component part of supramolecular chemistry, may be in its infancy of anesthetic application but recent advances have been described as novel and revolutionary. A review of current research coupled with an understanding of cyclodextrin properties is necessary to fully appreciate the current uses and future potentials of these unique molecules.http://dx.doi.org/10.1100/tsw.2007.83 |
| spellingShingle | Mark Welliver John P. McDonough Anesthetic Related Advances with Cyclodextrins The Scientific World Journal |
| title | Anesthetic Related Advances with Cyclodextrins |
| title_full | Anesthetic Related Advances with Cyclodextrins |
| title_fullStr | Anesthetic Related Advances with Cyclodextrins |
| title_full_unstemmed | Anesthetic Related Advances with Cyclodextrins |
| title_short | Anesthetic Related Advances with Cyclodextrins |
| title_sort | anesthetic related advances with cyclodextrins |
| url | http://dx.doi.org/10.1100/tsw.2007.83 |
| work_keys_str_mv | AT markwelliver anestheticrelatedadvanceswithcyclodextrins AT johnpmcdonough anestheticrelatedadvanceswithcyclodextrins |