Correlation of oral health of children with acute leukemia during the induction phase
Background: Treatment of acute leukemia′s- a common childhood malignancy, involves intensive and powerful multi-drug chemotherapeutic regime. Oral lesions are a common complication in these patients affecting oral health status. Aim: This study was conducted to evaluate and assess the oral health st...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2014-01-01
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| Series: | Indian Journal of Medical and Paediatric Oncology |
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| Online Access: | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2014;volume=35;issue=1;spage=36;epage=39;aulast=Dholam |
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| author | Kanchan P. Dholam Sandeep Gurav Jinesh Dugad Shripad Banavli |
| author_facet | Kanchan P. Dholam Sandeep Gurav Jinesh Dugad Shripad Banavli |
| author_sort | Kanchan P. Dholam |
| collection | DOAJ |
| description | Background: Treatment of acute leukemia′s- a common childhood malignancy, involves intensive and powerful multi-drug chemotherapeutic regime. Oral lesions are a common complication in these patients affecting oral health status. Aim: This study was conducted to evaluate and assess the oral health status of newly diagnosed leukemic pediatric patients during induction phase and its correlation to outcome of induction therapy. Material Methods: Oral examinations was done in 33 children between the age group of 5-15 years with acute lymphoblastic leukemia (ALL) and acute myloblastic leukemia (AML), who were undergoing chemotherapy. Oral Hygiene Index- Simplified, (OHI-S) decayed missing filled teeth index (def/DMFT), Loe and Sillness index for gingiva, and complete blood count at first and fourth week of induction phase were recorded for each patient. The changes in the oral health status were analyzed with Wilcoxon signed rank test. Results: During an induction phase it was observed that level of OHI-S (P = 0.002), Loe and Sillness index (P = 0.003), def/DMFT index (P = 0.076), platelet count (P = 0.00) increased significantly and no significant difference was noted in hemoglobin (P = 0.4) and total leucocytes count (P = 0.11). Conclusion: It was observed that, although oral health status had significantly worsened, the induction outcome was not affected. |
| format | Article |
| id | doaj-art-bd7f256ee08643c9a6f061fcbb63dd7e |
| institution | OA Journals |
| issn | 0971-5851 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Medical and Paediatric Oncology |
| spelling | doaj-art-bd7f256ee08643c9a6f061fcbb63dd7e2025-08-20T01:55:44ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58512014-01-01351363910.4103/0971-5851.133717Correlation of oral health of children with acute leukemia during the induction phaseKanchan P. DholamSandeep GuravJinesh DugadShripad BanavliBackground: Treatment of acute leukemia′s- a common childhood malignancy, involves intensive and powerful multi-drug chemotherapeutic regime. Oral lesions are a common complication in these patients affecting oral health status. Aim: This study was conducted to evaluate and assess the oral health status of newly diagnosed leukemic pediatric patients during induction phase and its correlation to outcome of induction therapy. Material Methods: Oral examinations was done in 33 children between the age group of 5-15 years with acute lymphoblastic leukemia (ALL) and acute myloblastic leukemia (AML), who were undergoing chemotherapy. Oral Hygiene Index- Simplified, (OHI-S) decayed missing filled teeth index (def/DMFT), Loe and Sillness index for gingiva, and complete blood count at first and fourth week of induction phase were recorded for each patient. The changes in the oral health status were analyzed with Wilcoxon signed rank test. Results: During an induction phase it was observed that level of OHI-S (P = 0.002), Loe and Sillness index (P = 0.003), def/DMFT index (P = 0.076), platelet count (P = 0.00) increased significantly and no significant difference was noted in hemoglobin (P = 0.4) and total leucocytes count (P = 0.11). Conclusion: It was observed that, although oral health status had significantly worsened, the induction outcome was not affected.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2014;volume=35;issue=1;spage=36;epage=39;aulast=DholamInduction phaseleukemiaoral hygieneoral lesions |
| spellingShingle | Kanchan P. Dholam Sandeep Gurav Jinesh Dugad Shripad Banavli Correlation of oral health of children with acute leukemia during the induction phase Indian Journal of Medical and Paediatric Oncology Induction phase leukemia oral hygiene oral lesions |
| title | Correlation of oral health of children with acute leukemia during the induction phase |
| title_full | Correlation of oral health of children with acute leukemia during the induction phase |
| title_fullStr | Correlation of oral health of children with acute leukemia during the induction phase |
| title_full_unstemmed | Correlation of oral health of children with acute leukemia during the induction phase |
| title_short | Correlation of oral health of children with acute leukemia during the induction phase |
| title_sort | correlation of oral health of children with acute leukemia during the induction phase |
| topic | Induction phase leukemia oral hygiene oral lesions |
| url | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2014;volume=35;issue=1;spage=36;epage=39;aulast=Dholam |
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