The N‐terminal domain of gasdermin D induces liver fibrosis by reprogrammed lipid metabolism
Abstract Background The emerging incidence of pathogenic liver conditions is turning into a major concern for global health. Induction of pyroptosis in hepatocytes instigates cellular disintegration, which in turn liberates substantial quantities of pro‐inflammatory intracellular substances, thereby...
Saved in:
Main Authors: | Xue Wang, Chunyou Ning, Xingyi Cheng, Zhengzhong Wu, Dongbo Wu, Xuemei Ding, Cunxiang Ju, Zhihang Zhou, Lingfeng Wan, Wei Zhao, Peiliang Shi |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2025-01-01
|
Series: | Animal Models and Experimental Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/ame2.12506 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Acrylamide exposure promotes the progression of depression-like behavior in mice with CUMS via GSDMD-mediated pyroptosis
by: JianFeng Liu, et al.
Published: (2025-01-01) -
Bushen Huoxue formula protects against renal fibrosis and pyroptosis in chronic kidney disease by inhibiting ROS/NLRP3-mediated inflammasome activation
by: Lin Liao, et al.
Published: (2024-12-01) -
Understanding the mechanisms of hypoxia-induced tissue damage in fish: The role of GasderminEa/b in Larimichthys crocea
by: Lin Wang, et al.
Published: (2025-01-01) -
The serum levels of gasdermin D in uremic patients and its relationship with the prognosis: a prospective observational cohort study
by: XiaPing Zhang, et al.
Published: (2024-12-01) -
Exploiting gasdermin-mediated pyroptosis for enhanced antimicrobial activity of phage endolysin against Pseudomonas aeruginosa
by: Dorota Kuc-Ciepluch, et al.
Published: (2025-01-01)