Maternal-Cord Blood Vitamin D Correlations Vary by Maternal Levels
Vitamin D levels of pregnant women and their neonates tend to be related; however, it is unknown whether there are any subgroups in which they are not related. 25-Hydroxyvitamin D [25(OH)D] was measured in prenatal maternal and child cord blood samples of participants (n=241 pairs) in a birth cohort...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Journal of Pregnancy |
| Online Access: | http://dx.doi.org/10.1155/2016/7474192 |
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| author | Ganesa Wegienka Hareena Kaur Roopina Sangha Andrea E. Cassidy-Bushrow |
| author_facet | Ganesa Wegienka Hareena Kaur Roopina Sangha Andrea E. Cassidy-Bushrow |
| author_sort | Ganesa Wegienka |
| collection | DOAJ |
| description | Vitamin D levels of pregnant women and their neonates tend to be related; however, it is unknown whether there are any subgroups in which they are not related. 25-Hydroxyvitamin D [25(OH)D] was measured in prenatal maternal and child cord blood samples of participants (n=241 pairs) in a birth cohort. Spearman correlations were examined within subgroups defined by prenatal and delivery factors. Cord blood as a percentage of prenatal 25(OH)D level was calculated and characteristics compared between those who did and did not have ≥25% and ≥50% of the maternal level and those who did and did not have a detectable 25(OH)D level. The correlation among Black children was lower than in White children. When the maternal 25(OH)D level was <15 ng/mL, the overall correlation was r=0.16. Most children had a 25(OH)D cord blood level less than half of their mother’s; 15.4% had a level that was <25% of their mother’s. Winter birth and maternal level were associated with the level being less than 25%. Children with undetectable levels were more likely to be Black and less likely to be firstborn. These data suggest mothers may reduce their contribution to the fetus’s 25(OH)D supply once their own level becomes low. |
| format | Article |
| id | doaj-art-bd50d3b3a7714c17bd2d6e974238eeb4 |
| institution | Kabale University |
| issn | 2090-2727 2090-2735 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Pregnancy |
| spelling | doaj-art-bd50d3b3a7714c17bd2d6e974238eeb42025-02-03T06:12:40ZengWileyJournal of Pregnancy2090-27272090-27352016-01-01201610.1155/2016/74741927474192Maternal-Cord Blood Vitamin D Correlations Vary by Maternal LevelsGanesa Wegienka0Hareena Kaur1Roopina Sangha2Andrea E. Cassidy-Bushrow3Department of Public Health Sciences, Henry Ford Hospital, Detroit, MI 48202, USADepartment of Public Health Sciences, Henry Ford Hospital, Detroit, MI 48202, USADepartment of Women’s Health, Henry Ford Hospital, Detroit, MI 48202, USADepartment of Public Health Sciences, Henry Ford Hospital, Detroit, MI 48202, USAVitamin D levels of pregnant women and their neonates tend to be related; however, it is unknown whether there are any subgroups in which they are not related. 25-Hydroxyvitamin D [25(OH)D] was measured in prenatal maternal and child cord blood samples of participants (n=241 pairs) in a birth cohort. Spearman correlations were examined within subgroups defined by prenatal and delivery factors. Cord blood as a percentage of prenatal 25(OH)D level was calculated and characteristics compared between those who did and did not have ≥25% and ≥50% of the maternal level and those who did and did not have a detectable 25(OH)D level. The correlation among Black children was lower than in White children. When the maternal 25(OH)D level was <15 ng/mL, the overall correlation was r=0.16. Most children had a 25(OH)D cord blood level less than half of their mother’s; 15.4% had a level that was <25% of their mother’s. Winter birth and maternal level were associated with the level being less than 25%. Children with undetectable levels were more likely to be Black and less likely to be firstborn. These data suggest mothers may reduce their contribution to the fetus’s 25(OH)D supply once their own level becomes low.http://dx.doi.org/10.1155/2016/7474192 |
| spellingShingle | Ganesa Wegienka Hareena Kaur Roopina Sangha Andrea E. Cassidy-Bushrow Maternal-Cord Blood Vitamin D Correlations Vary by Maternal Levels Journal of Pregnancy |
| title | Maternal-Cord Blood Vitamin D Correlations Vary by Maternal Levels |
| title_full | Maternal-Cord Blood Vitamin D Correlations Vary by Maternal Levels |
| title_fullStr | Maternal-Cord Blood Vitamin D Correlations Vary by Maternal Levels |
| title_full_unstemmed | Maternal-Cord Blood Vitamin D Correlations Vary by Maternal Levels |
| title_short | Maternal-Cord Blood Vitamin D Correlations Vary by Maternal Levels |
| title_sort | maternal cord blood vitamin d correlations vary by maternal levels |
| url | http://dx.doi.org/10.1155/2016/7474192 |
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