Evaluating the potential of Kalanchoe pinnata, Piper amalago amalago, and other botanicals as economical insecticidal synergists against Anopheles gambiae

Evaluating the potential of Kalanchoe pinnata, Piper amalago amalago, and other botanicals as economical insecticidal synergists against Anopheles gambiae

Abstract Background Synergists reduce insecticide metabolism in mosquitoes by competing with insecticides for the active sites of metabolic enzymes, such as cytochrome P450s (CYPs). This increases the availability of the insecticide at its specific target site. The combination of both insecticides a...

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Bibliographic Details
Main Authors: Sheena Francis, William Irvine, Lucy Mackenzie-Impoinvil, Lucrecia Vizcaino, Rodolphe Poupardin, Audrey Lenhart, Mark J. I. Paine, Rupika Delgoda
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Malaria Journal
Subjects:
Jamaican plants
Kalanchoe (Bryophyllum) pinnata
Piper amalago var. amalago
CYP
Mosquitoes
RNA-seq
Online Access:https://doi.org/10.1186/s12936-025-05254-4
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