The MMP-1/PAR-1 Axis Enhances Proliferation and Neuronal Differentiation of Adult Hippocampal Neural Progenitor Cells
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that play a role in varied forms of developmental and postnatal neuroplasticity. MMP substrates include protease-activated receptor-1 (PAR-1), a G-protein coupled receptor expressed in hippocampus. We examined proliferation and diffe...
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Main Authors: | Maria Maddalena Valente, Megan Allen, Valeria Bortolotto, Seung T. Lim, Katherine Conant, Mariagrazia Grilli |
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Format: | Article |
Language: | English |
Published: |
Wiley
2015-01-01
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Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/2015/646595 |
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