NLRP3 activation maintains intestinal epithelial barrier and reduces liver injury in alcoholic liver disease mice

NLRP3 activation maintains intestinal epithelial barrier and reduces liver injury in alcoholic liver disease mice

Abstract Background Alcoholic liver disease (ALD) patients with bacterial infections usually exhibit high mortality rates. Infections frequently involve bacteria such as Vibrio vulnificus and Enterococcus faecalis. Nevertheless, the mechanisms predisposing ALD patients to bacterial infections and th...

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Bibliographic Details
Main Authors: Shi‐Qing Li, Ya‐Ru Wang, Zhong‐Liang Xie, Yan Wang, Zi‐Han Feng, Jian‐Hao Xu, Bing Yuan, Yi‐Tong Zhang, Guan Yang, Jing‐Lin Wang, Yuan Yuan
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Clinical and Translational Medicine
Subjects:
alcoholic liver disease
intestinal epithelial barrier
NLRP3 inflammasome
Vibrio infection
Online Access:https://doi.org/10.1002/ctm2.70099
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