The Role of Imaging in Patient Selection, Preoperative Planning, and Postoperative Monitoring in Human Upper Extremity Allotransplantation

Objective. To describe the role of imaging in vascular composite allotransplantation based on one institution’s experience with upper extremity allotransplant patients. Methods. The institutional review board approved this review of HIPAA-compliant patient data without the need for individual consen...

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Main Authors: Eira S. Roth, David G. Buck, Vijay S. Gorantla, Joseph E. Losee, Daniel E. Foust, Cynthia A. Britton
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Transplantation
Online Access:http://dx.doi.org/10.1155/2014/169546
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author Eira S. Roth
David G. Buck
Vijay S. Gorantla
Joseph E. Losee
Daniel E. Foust
Cynthia A. Britton
author_facet Eira S. Roth
David G. Buck
Vijay S. Gorantla
Joseph E. Losee
Daniel E. Foust
Cynthia A. Britton
author_sort Eira S. Roth
collection DOAJ
description Objective. To describe the role of imaging in vascular composite allotransplantation based on one institution’s experience with upper extremity allotransplant patients. Methods. The institutional review board approved this review of HIPAA-compliant patient data without the need for individual consent. A retrospective review was performed of imaging from 2008 to 2011 on individuals undergoing upper extremity transplantation. This demonstrated that, of the 19 patients initially considered, 5 patients with a mean age of 37 underwent transplantation. Reports were correlated clinically to delineate which preoperative factors lead to patient selection versus disqualification and what concerns dictated postoperative imaging. Findings were subdivided into musculoskeletal and vascular imaging criterion. Results. Within the screening phase, musculoskeletal exclusion criterion included severe shoulder arthropathy, poor native bone integrity, and marked muscular atrophy. Vascular exclusion criterion included loss of sufficient arterial or venous supply and significant distortion of the native vascular architecture. Postoperative imaging was used to document healing and hardware integrity. Postsurgical angiography and ultrasound were used to monitor for endothelial proliferation or thrombosis as signs of rejection and vascular complication. Conclusion. Multimodality imaging is an integral component of vascular composite allotransplantation surgical planning and surveillance to maximize returning form and functionality while minimizing possible complications.
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publishDate 2014-01-01
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series Journal of Transplantation
spelling doaj-art-bced91b0ac3347c2995dd11eb3bc23ce2025-02-03T05:48:08ZengWileyJournal of Transplantation2090-00072090-00152014-01-01201410.1155/2014/169546169546The Role of Imaging in Patient Selection, Preoperative Planning, and Postoperative Monitoring in Human Upper Extremity AllotransplantationEira S. Roth0David G. Buck1Vijay S. Gorantla2Joseph E. Losee3Daniel E. Foust4Cynthia A. Britton5Department of Diagnostic Radiology, University of Pittsburgh Medical Center (UPMC), C/o Patricia O’Kelly, 200 Lothrop Street Presbyterian South Tower Suite 3950, Pittsburgh, PA 15213, USADepartment of Interventional Radiology, The Western Pennsylvania Hospital, 4800 Friendship Avenue, Pittsburgh, PA 14224, USADepartment of Plastic Surgery, University of Pittsburgh Medical Center, 3550 Terrace Street Scaife Hall, Suite 678, Pittsburgh, PA 15261, USADepartment of Plastic Surgery, University of Pittsburgh Medical Center, 3550 Terrace Street Scaife Hall, Suite 678, Pittsburgh, PA 15261, USADepartment of Plastic Surgery, University of Pittsburgh Medical Center, 3550 Terrace Street Scaife Hall, Suite 678, Pittsburgh, PA 15261, USADepartment of Diagnostic Radiology, University of Pittsburgh Medical Center (UPMC), C/o Patricia O’Kelly, 200 Lothrop Street Presbyterian South Tower Suite 3950, Pittsburgh, PA 15213, USAObjective. To describe the role of imaging in vascular composite allotransplantation based on one institution’s experience with upper extremity allotransplant patients. Methods. The institutional review board approved this review of HIPAA-compliant patient data without the need for individual consent. A retrospective review was performed of imaging from 2008 to 2011 on individuals undergoing upper extremity transplantation. This demonstrated that, of the 19 patients initially considered, 5 patients with a mean age of 37 underwent transplantation. Reports were correlated clinically to delineate which preoperative factors lead to patient selection versus disqualification and what concerns dictated postoperative imaging. Findings were subdivided into musculoskeletal and vascular imaging criterion. Results. Within the screening phase, musculoskeletal exclusion criterion included severe shoulder arthropathy, poor native bone integrity, and marked muscular atrophy. Vascular exclusion criterion included loss of sufficient arterial or venous supply and significant distortion of the native vascular architecture. Postoperative imaging was used to document healing and hardware integrity. Postsurgical angiography and ultrasound were used to monitor for endothelial proliferation or thrombosis as signs of rejection and vascular complication. Conclusion. Multimodality imaging is an integral component of vascular composite allotransplantation surgical planning and surveillance to maximize returning form and functionality while minimizing possible complications.http://dx.doi.org/10.1155/2014/169546
spellingShingle Eira S. Roth
David G. Buck
Vijay S. Gorantla
Joseph E. Losee
Daniel E. Foust
Cynthia A. Britton
The Role of Imaging in Patient Selection, Preoperative Planning, and Postoperative Monitoring in Human Upper Extremity Allotransplantation
Journal of Transplantation
title The Role of Imaging in Patient Selection, Preoperative Planning, and Postoperative Monitoring in Human Upper Extremity Allotransplantation
title_full The Role of Imaging in Patient Selection, Preoperative Planning, and Postoperative Monitoring in Human Upper Extremity Allotransplantation
title_fullStr The Role of Imaging in Patient Selection, Preoperative Planning, and Postoperative Monitoring in Human Upper Extremity Allotransplantation
title_full_unstemmed The Role of Imaging in Patient Selection, Preoperative Planning, and Postoperative Monitoring in Human Upper Extremity Allotransplantation
title_short The Role of Imaging in Patient Selection, Preoperative Planning, and Postoperative Monitoring in Human Upper Extremity Allotransplantation
title_sort role of imaging in patient selection preoperative planning and postoperative monitoring in human upper extremity allotransplantation
url http://dx.doi.org/10.1155/2014/169546
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