Targeting Glioma Stem Cells: Therapeutic Opportunities and Challenges

Glioblastoma (GBM), or grade 4 glioma, is the most common and aggressive primary brain tumor in adults with a median survival of 15 months. Increasing evidence suggests that GBM’s aggressiveness, invasiveness, and therapy resistance are driven by glioma stem cells (GSCs), a subpopulation of tumor ce...

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Bibliographic Details
Main Authors: Asma Mahdi, Mohamed Aittaleb, Fadel Tissir
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/14/9/675
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