Liver Cell Death: Update on Apoptosis
Hepatocyte cell death is a cardinal feature of almost every liver disease. Apoptosis is a mode of cell death characterized by specific morphological and biochemical features. Over the past decade, the importance of apoptosis has been appreciated, and it is now thought to be the main mode of cell dea...
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| Format: | Article |
| Language: | English |
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Wiley
2003-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2003/205751 |
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| _version_ | 1832567056642342912 |
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| author | Marc Bilodeau |
| author_facet | Marc Bilodeau |
| author_sort | Marc Bilodeau |
| collection | DOAJ |
| description | Hepatocyte cell death is a cardinal feature of almost every liver disease. Apoptosis is a mode of cell death characterized by specific morphological and biochemical features. Over the past decade, the importance of apoptosis has been appreciated, and it is now thought to be the main mode of cell death in liver diseases. The recognition that apoptosis can be modulated by the cell itself or by the extracellular environment has given hope that treatments can be designed to modify the evolution of disease. This article presents an overview of this important phenomenon, as well as models of hepatocyte apoptosis and goals of current research. The significance of apoptosis to the pathophysiology of liver disease is discussed. |
| format | Article |
| id | doaj-art-bcb37052f40047ecbcc5157ca9e74141 |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 2003-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-bcb37052f40047ecbcc5157ca9e741412025-02-03T01:02:30ZengWileyCanadian Journal of Gastroenterology0835-79002003-01-0117850150610.1155/2003/205751Liver Cell Death: Update on ApoptosisMarc Bilodeau0Centre de recherche du Centre Hospitalier de l'Universite de Montreal (CHUM), Hôpital Saint-Luc, Laboratoire d’hépatologie cellulaire, Montreal, Quebec, CanadaHepatocyte cell death is a cardinal feature of almost every liver disease. Apoptosis is a mode of cell death characterized by specific morphological and biochemical features. Over the past decade, the importance of apoptosis has been appreciated, and it is now thought to be the main mode of cell death in liver diseases. The recognition that apoptosis can be modulated by the cell itself or by the extracellular environment has given hope that treatments can be designed to modify the evolution of disease. This article presents an overview of this important phenomenon, as well as models of hepatocyte apoptosis and goals of current research. The significance of apoptosis to the pathophysiology of liver disease is discussed.http://dx.doi.org/10.1155/2003/205751 |
| spellingShingle | Marc Bilodeau Liver Cell Death: Update on Apoptosis Canadian Journal of Gastroenterology |
| title | Liver Cell Death: Update on Apoptosis |
| title_full | Liver Cell Death: Update on Apoptosis |
| title_fullStr | Liver Cell Death: Update on Apoptosis |
| title_full_unstemmed | Liver Cell Death: Update on Apoptosis |
| title_short | Liver Cell Death: Update on Apoptosis |
| title_sort | liver cell death update on apoptosis |
| url | http://dx.doi.org/10.1155/2003/205751 |
| work_keys_str_mv | AT marcbilodeau livercelldeathupdateonapoptosis |