Longitudinal fecal microbiota and volatile metabolomics preceding necrotizing enterocolitis in preterm infants: a case–control study

Longitudinal fecal microbiota and volatile metabolomics preceding necrotizing enterocolitis in preterm infants: a case–control study

Abstract Alterations in fecal microbiota and volatile organic compound (VOC) profiles of preterm infants have been demonstrated before onset of necrotizing enterocolitis (NEC). However, NEC-specific signatures need to be identified before potential application as predictive biomarker in clinical pra...

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Main Authors: S. el Manouni el Hassani, N. M. Frerichs, D. J. C. Berkhout, T. Nijsen, H. H. Knobel, H. Weda, M. Xu, X. Long, L. Wijnoltz, M. M. van Weissenbruch, A. H. van Kaam, V. Cossey, C. F. W. Peeters, R. A. van Lingen, C. V. Hulzebos, D. C. Vijlbrief, W. P. de Boode, B. W. Kramer, A. E. Budding, M. A. Benninga, N. K. H. de Boer, H. J. Niemarkt, T. G. J. de Meij
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Metabolomics
Volatile organic compounds
Microbiome
Stool
Necrotizing enterocolitis
Online Access:https://doi.org/10.1038/s41598-025-94692-w
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