Protocol for synthesizing, implanting, and using polydimethylsiloxane as skull replacement in mice for imaging, electrophysiology, and optogenetics
Summary: Many techniques to record and manipulate neuronal activity across large portions of the vertebrate brain are now available. However, few effective approaches enable both optical and mechanical access to the brain. Here, we present a protocol for synthesizing, implanting, and using polydimet...
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| Main Authors: | Kengo Takahashi, Gerjan Huis in ‘t Veld, Davide Benedetti, Jun-Ying Wang, Samuel Pontes Quero, Rafael Yuste, Cyriel M.A. Pennartz, Umberto Olcese |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-09-01
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| Series: | STAR Protocols |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666166725003703 |
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