Correlations among fatigue, respiratory function, balance and core muscle morphology in multiple sclerosis: a comprehensive observational study
BackgroundRecent scientific interest has focused on exploring the potential relationships between fatigue, respiratory function and balance in multiple sclerosis (MS) subjects. While some studies suggest that fatigue may impact respiratory function and postural stability, the exact nature of these a...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2024.1529057/full |
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| author | Marta De La Plaza San Frutos Ismael Sanz-Esteban Ismael Sanz-Esteban Federico Salniccia Federico Salniccia Alberto Bermejo-Franco Alberto Bermejo-Franco Ameyalli García-Corona María Cristina Palma-Baquedano Marina Castel-Sánchez Marina Castel-Sánchez Cecilia Estrada-Barranco Cecilia Estrada-Barranco |
| author_facet | Marta De La Plaza San Frutos Ismael Sanz-Esteban Ismael Sanz-Esteban Federico Salniccia Federico Salniccia Alberto Bermejo-Franco Alberto Bermejo-Franco Ameyalli García-Corona María Cristina Palma-Baquedano Marina Castel-Sánchez Marina Castel-Sánchez Cecilia Estrada-Barranco Cecilia Estrada-Barranco |
| author_sort | Marta De La Plaza San Frutos |
| collection | DOAJ |
| description | BackgroundRecent scientific interest has focused on exploring the potential relationships between fatigue, respiratory function and balance in multiple sclerosis (MS) subjects. While some studies suggest that fatigue may impact respiratory function and postural stability, the exact nature of these associations remains under investigation. Ultrasound imaging is increasingly being used to examine the structural and functional characteristics of core muscles, aiming to better understand how these variables might be interconnected. Understanding these associations is crucial for developing targeted interventions to enhance overall physical performance in this population. This study examines the relationship between fatigue, respiratory function, balance, and ultrasound variables of abdominal musculature in MS.MethodsA cross-sectional study was conducted involving 27 subjects diagnosed with MS, comprising 17 females and 10 males. Study variables were: fatigue (Modified Fatigue Impact Scale—MFIS); respiratory function (Forced Vital Capacity—FVC and Forced Expiratory Volume in the first second—FEV1); balance (Berg Balance Scale—BBS and Trunk Impairment Scale Dynamic—TIS DYN); and ultrasound measurements of abdominal and diaphragmatic musculature. Correlations were analyzed using Spearman’s correlation, with a statistical significance level of p < 0.05.ResultsSignificant correlations were found between respiratory function and balance scores. FVC showed a moderate correlation with BBS (r = 0.443), while FEV1 had a high correlation with BBS (r = 0.500) and a moderate correlation with TIS DYN (r = 0.427). MFIS showed a moderate negative correlation with BBS (r = −0.402). The strength and function of the central abdominal musculature, particularly the internal oblique, were crucial for trunk stability and postural control.ConclusionThese findings highlight the interplay between respiratory function, balance, fatigue, and abdominal muscle morphology in MS, emphasizing the potential benefits of interventions targeting respiratory function to improve balance and reduce fatigue, ultimately enhancing quality of life in this population. |
| format | Article |
| id | doaj-art-bc989da2367b4ddfb651ebe77967355a |
| institution | Kabale University |
| issn | 1664-2295 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Neurology |
| spelling | doaj-art-bc989da2367b4ddfb651ebe77967355a2025-01-20T15:37:31ZengFrontiers Media S.A.Frontiers in Neurology1664-22952025-01-011510.3389/fneur.2024.15290571529057Correlations among fatigue, respiratory function, balance and core muscle morphology in multiple sclerosis: a comprehensive observational studyMarta De La Plaza San Frutos0Ismael Sanz-Esteban1Ismael Sanz-Esteban2Federico Salniccia3Federico Salniccia4Alberto Bermejo-Franco5Alberto Bermejo-Franco6Ameyalli García-Corona7María Cristina Palma-Baquedano8Marina Castel-Sánchez9Marina Castel-Sánchez10Cecilia Estrada-Barranco11Cecilia Estrada-Barranco12Department of Physiotherapy, Faculty of Medicine, Health and Sports, European University of Madrid, Madrid, SpainDepartment of Physiotherapy, Faculty of Medicine, Health and Sports, European University of Madrid, Madrid, SpainNeurosciences and Physical Therapy Research Group, Madrid, SpainDepartment of Physiotherapy, Faculty of Medicine, Health and Sports, European University of Madrid, Madrid, SpainNeurosciences and Physical Therapy Research Group, Madrid, SpainDepartment of Physiotherapy, Faculty of Medicine, Health and Sports, European University of Madrid, Madrid, SpainNeurosciences and Physical Therapy Research Group, Madrid, SpainDepartment of Physiotherapy, Faculty of Medicine, Health and Sports, European University of Madrid, Madrid, SpainDepartment of Physiotherapy, Faculty of Medicine, Health and Sports, European University of Madrid, Madrid, SpainDepartment of Physiotherapy, Faculty of Medicine, Health and Sports, European University of Madrid, Madrid, SpainNeurosciences and Physical Therapy Research Group, Madrid, SpainDepartment of Physiotherapy, Faculty of Medicine, Health and Sports, European University of Madrid, Madrid, SpainNeurosciences and Physical Therapy Research Group, Madrid, SpainBackgroundRecent scientific interest has focused on exploring the potential relationships between fatigue, respiratory function and balance in multiple sclerosis (MS) subjects. While some studies suggest that fatigue may impact respiratory function and postural stability, the exact nature of these associations remains under investigation. Ultrasound imaging is increasingly being used to examine the structural and functional characteristics of core muscles, aiming to better understand how these variables might be interconnected. Understanding these associations is crucial for developing targeted interventions to enhance overall physical performance in this population. This study examines the relationship between fatigue, respiratory function, balance, and ultrasound variables of abdominal musculature in MS.MethodsA cross-sectional study was conducted involving 27 subjects diagnosed with MS, comprising 17 females and 10 males. Study variables were: fatigue (Modified Fatigue Impact Scale—MFIS); respiratory function (Forced Vital Capacity—FVC and Forced Expiratory Volume in the first second—FEV1); balance (Berg Balance Scale—BBS and Trunk Impairment Scale Dynamic—TIS DYN); and ultrasound measurements of abdominal and diaphragmatic musculature. Correlations were analyzed using Spearman’s correlation, with a statistical significance level of p < 0.05.ResultsSignificant correlations were found between respiratory function and balance scores. FVC showed a moderate correlation with BBS (r = 0.443), while FEV1 had a high correlation with BBS (r = 0.500) and a moderate correlation with TIS DYN (r = 0.427). MFIS showed a moderate negative correlation with BBS (r = −0.402). The strength and function of the central abdominal musculature, particularly the internal oblique, were crucial for trunk stability and postural control.ConclusionThese findings highlight the interplay between respiratory function, balance, fatigue, and abdominal muscle morphology in MS, emphasizing the potential benefits of interventions targeting respiratory function to improve balance and reduce fatigue, ultimately enhancing quality of life in this population.https://www.frontiersin.org/articles/10.3389/fneur.2024.1529057/fullmultiple sclerosisfatiguerespiratory functionbalanceultrasoundabdominal muscles |
| spellingShingle | Marta De La Plaza San Frutos Ismael Sanz-Esteban Ismael Sanz-Esteban Federico Salniccia Federico Salniccia Alberto Bermejo-Franco Alberto Bermejo-Franco Ameyalli García-Corona María Cristina Palma-Baquedano Marina Castel-Sánchez Marina Castel-Sánchez Cecilia Estrada-Barranco Cecilia Estrada-Barranco Correlations among fatigue, respiratory function, balance and core muscle morphology in multiple sclerosis: a comprehensive observational study Frontiers in Neurology multiple sclerosis fatigue respiratory function balance ultrasound abdominal muscles |
| title | Correlations among fatigue, respiratory function, balance and core muscle morphology in multiple sclerosis: a comprehensive observational study |
| title_full | Correlations among fatigue, respiratory function, balance and core muscle morphology in multiple sclerosis: a comprehensive observational study |
| title_fullStr | Correlations among fatigue, respiratory function, balance and core muscle morphology in multiple sclerosis: a comprehensive observational study |
| title_full_unstemmed | Correlations among fatigue, respiratory function, balance and core muscle morphology in multiple sclerosis: a comprehensive observational study |
| title_short | Correlations among fatigue, respiratory function, balance and core muscle morphology in multiple sclerosis: a comprehensive observational study |
| title_sort | correlations among fatigue respiratory function balance and core muscle morphology in multiple sclerosis a comprehensive observational study |
| topic | multiple sclerosis fatigue respiratory function balance ultrasound abdominal muscles |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2024.1529057/full |
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