Management of Neuraxial Analgesia in a Parturient with Factor XIII Deficiency: A Case Report and Proposed Management Algorithm
Factor XIII (FXIII) deficiency is a rare coagulation defect that can be associated with significant bleeding. A 28-year-old pregnant woman, with a history of hemorrhagic stroke secondary to severe congenital FXIII deficiency, presented in active labor requesting an epidural. Factor XIII levels had b...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Anesthesiology |
| Online Access: | http://dx.doi.org/10.1155/2020/8892225 |
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| author | David B. Carroll Conrad Myler Natthapol Songdej Khaled Sedeek Dmitri Bezinover |
| author_facet | David B. Carroll Conrad Myler Natthapol Songdej Khaled Sedeek Dmitri Bezinover |
| author_sort | David B. Carroll |
| collection | DOAJ |
| description | Factor XIII (FXIII) deficiency is a rare coagulation defect that can be associated with significant bleeding. A 28-year-old pregnant woman, with a history of hemorrhagic stroke secondary to severe congenital FXIII deficiency, presented in active labor requesting an epidural. Factor XIII levels had been monitored throughout her pregnancy and treated with intermittent factor XIII infusions to maintain factor levels above 30% of normal. After careful multidisciplinary peripartum evaluation and FXIII replacement, neuraxial analgesia was performed without complication. Neuraxial analgesia can be performed without complication in patients with FXIII deficiency if FXIII levels are carefully managed and no other coagulopathy exists. |
| format | Article |
| id | doaj-art-bc88685782f1449fa009b8cfcc16bded |
| institution | Kabale University |
| issn | 2090-6382 2090-6390 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Anesthesiology |
| spelling | doaj-art-bc88685782f1449fa009b8cfcc16bded2025-02-03T06:06:45ZengWileyCase Reports in Anesthesiology2090-63822090-63902020-01-01202010.1155/2020/88922258892225Management of Neuraxial Analgesia in a Parturient with Factor XIII Deficiency: A Case Report and Proposed Management AlgorithmDavid B. Carroll0Conrad Myler1Natthapol Songdej2Khaled Sedeek3Dmitri Bezinover4Department of Anesthesiology and Perioperative Medicine, Milton S. Hershey Medical Canter, 500 University Dr, Hershey, PA 17033, USADepartment of Anesthesiology and Perioperative Medicine, Milton S. Hershey Medical Canter, 500 University Dr, Hershey, PA 17033, USADepartment of Medicine, Division of Hematology and Oncology, Milton S. Hershey Medical Center, 500 University Dr, Hershey, PA 17033, USADepartment of Anesthesiology and Perioperative Medicine, Milton S. Hershey Medical Canter, 500 University Dr, Hershey, PA 17033, USADepartment of Anesthesiology and Perioperative Medicine, Milton S. Hershey Medical Canter, 500 University Dr, Hershey, PA 17033, USAFactor XIII (FXIII) deficiency is a rare coagulation defect that can be associated with significant bleeding. A 28-year-old pregnant woman, with a history of hemorrhagic stroke secondary to severe congenital FXIII deficiency, presented in active labor requesting an epidural. Factor XIII levels had been monitored throughout her pregnancy and treated with intermittent factor XIII infusions to maintain factor levels above 30% of normal. After careful multidisciplinary peripartum evaluation and FXIII replacement, neuraxial analgesia was performed without complication. Neuraxial analgesia can be performed without complication in patients with FXIII deficiency if FXIII levels are carefully managed and no other coagulopathy exists.http://dx.doi.org/10.1155/2020/8892225 |
| spellingShingle | David B. Carroll Conrad Myler Natthapol Songdej Khaled Sedeek Dmitri Bezinover Management of Neuraxial Analgesia in a Parturient with Factor XIII Deficiency: A Case Report and Proposed Management Algorithm Case Reports in Anesthesiology |
| title | Management of Neuraxial Analgesia in a Parturient with Factor XIII Deficiency: A Case Report and Proposed Management Algorithm |
| title_full | Management of Neuraxial Analgesia in a Parturient with Factor XIII Deficiency: A Case Report and Proposed Management Algorithm |
| title_fullStr | Management of Neuraxial Analgesia in a Parturient with Factor XIII Deficiency: A Case Report and Proposed Management Algorithm |
| title_full_unstemmed | Management of Neuraxial Analgesia in a Parturient with Factor XIII Deficiency: A Case Report and Proposed Management Algorithm |
| title_short | Management of Neuraxial Analgesia in a Parturient with Factor XIII Deficiency: A Case Report and Proposed Management Algorithm |
| title_sort | management of neuraxial analgesia in a parturient with factor xiii deficiency a case report and proposed management algorithm |
| url | http://dx.doi.org/10.1155/2020/8892225 |
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