Persistent postremission clonal hematopoiesis shapes the relapse trajectories of acute myeloid leukemia

Abstract: Mutations found in acute myeloid leukemia (AML) such as DNMT3A, TET2, and ASXL1 can be found in the peripheral blood of healthy adults, a phenomenon termed clonal hematopoiesis (CH). These mutations are thought to represent the earliest genetic events in the evolution of AML. Genomic studi...

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Bibliographic Details
Main Authors: Ryan D. Chow, Priya Velu, Safoora Deihimi, Jonathan Belman, Angela Youn, Nisargbhai Shah, Selina M. Luger, Martin P. Carroll, Jennifer Morrissette, Robert L. Bowman
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952925001016
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