TEN in a Case of SLE - A case based review

Systemic lupus erythematosus (SLE) is a complex autoimmune disorder of unknown etiology. Cutaneous manifestations in SLE are common, results in significant morbidity and helpful in diagnosis of underlying systemic disease. Vesiculobullous lesions in SLE are uncommon but present a diagnostic challeng...

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Main Authors: Shekhar Neema, Sehdev Singh, Abhishek Kumar, S Radhakrishnan
Format: Article
Language:English
Published: SAGE Publishing 2020-01-01
Series:Indian Journal of Rheumatology
Subjects:
Online Access:http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2020;volume=15;issue=1;spage=56;epage=58;aulast=Neema
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author Shekhar Neema
Sehdev Singh
Abhishek Kumar
S Radhakrishnan
author_facet Shekhar Neema
Sehdev Singh
Abhishek Kumar
S Radhakrishnan
author_sort Shekhar Neema
collection DOAJ
description Systemic lupus erythematosus (SLE) is a complex autoimmune disorder of unknown etiology. Cutaneous manifestations in SLE are common, results in significant morbidity and helpful in diagnosis of underlying systemic disease. Vesiculobullous lesions in SLE are uncommon but present a diagnostic challenge. It can be a manifestation of SLE-specific or nonspecific pathology. It can also result from unrelated etiology such as drug-induced toxic epidermal necrolysis (TEN). Clinically, it is challenging to differentiate TEN-like acute cutaneous lupus erythematosus from classical TEN. We hereby present a case of TEN in SLE and discuss approach to vesiculobullous lesions in SLE.
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publishDate 2020-01-01
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series Indian Journal of Rheumatology
spelling doaj-art-bc79d56bdf6f4ebe9c06bebbc758a06b2025-08-20T01:47:50ZengSAGE PublishingIndian Journal of Rheumatology0973-36980973-37012020-01-01151565810.4103/injr.injr_139_19TEN in a Case of SLE - A case based reviewShekhar NeemaSehdev SinghAbhishek KumarS RadhakrishnanSystemic lupus erythematosus (SLE) is a complex autoimmune disorder of unknown etiology. Cutaneous manifestations in SLE are common, results in significant morbidity and helpful in diagnosis of underlying systemic disease. Vesiculobullous lesions in SLE are uncommon but present a diagnostic challenge. It can be a manifestation of SLE-specific or nonspecific pathology. It can also result from unrelated etiology such as drug-induced toxic epidermal necrolysis (TEN). Clinically, it is challenging to differentiate TEN-like acute cutaneous lupus erythematosus from classical TEN. We hereby present a case of TEN in SLE and discuss approach to vesiculobullous lesions in SLE.http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2020;volume=15;issue=1;spage=56;epage=58;aulast=Neemaacute cutaneous lupus erythematosussystemic lupus erythematosustoxic epidermal necrolysis
spellingShingle Shekhar Neema
Sehdev Singh
Abhishek Kumar
S Radhakrishnan
TEN in a Case of SLE - A case based review
Indian Journal of Rheumatology
acute cutaneous lupus erythematosus
systemic lupus erythematosus
toxic epidermal necrolysis
title TEN in a Case of SLE - A case based review
title_full TEN in a Case of SLE - A case based review
title_fullStr TEN in a Case of SLE - A case based review
title_full_unstemmed TEN in a Case of SLE - A case based review
title_short TEN in a Case of SLE - A case based review
title_sort ten in a case of sle a case based review
topic acute cutaneous lupus erythematosus
systemic lupus erythematosus
toxic epidermal necrolysis
url http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2020;volume=15;issue=1;spage=56;epage=58;aulast=Neema
work_keys_str_mv AT shekharneema teninacaseofsleacasebasedreview
AT sehdevsingh teninacaseofsleacasebasedreview
AT abhishekkumar teninacaseofsleacasebasedreview
AT sradhakrishnan teninacaseofsleacasebasedreview