Mania Induced by a Low Dose of Citalopram: A Case Report
Background: Antidepressant-induced mania is commonly observed in contemporary clinical practice. The problem in patients with unipolar depression has been evident since the introduction of the first antidepressants. Selective serotonin reuptake inhibitors (SSRIs), as new drugs, are one of those drug...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Jaypee Brothers Medical Publisher
2024-01-01
|
| Series: | Indian Journal of Private Psychiatry |
| Subjects: | |
| Online Access: | https://www.ijiapp.com/doi/IJPP/pdf/10.5005/jp-journals-10067-0160 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849763433528950784 |
|---|---|
| author | Jaafar Omer Ahmed Koyar Sherko M Salih Makwan Mohammed Abdulkareem |
| author_facet | Jaafar Omer Ahmed Koyar Sherko M Salih Makwan Mohammed Abdulkareem |
| author_sort | Jaafar Omer Ahmed |
| collection | DOAJ |
| description | Background: Antidepressant-induced mania is commonly observed in contemporary clinical practice. The problem in patients with unipolar depression has been evident since the introduction of the first antidepressants. Selective serotonin reuptake inhibitors (SSRIs), as new drugs, are one of those drugs that may lead to treatment-induced mania. The risk of inducing mania in bipolar patients with citalopram is comparable to the documented risk with other SSRIs. This case study elucidates the crucial factors for distinguishing key depressive episodes between bipolar and unipolar depression and provides recommendations regarding the use of antidepressants in high-risk patients.
Case presentation: A 24-year-old Kurdish woman developed mania after self-administering a low dose of Citalopram for depression. Diana Azad (DA) is a 24-year-old single female. She was referred to the Mental Health Treatment Center by the police under a judicial order for psychiatric assessment and treatment. DA was irritable, aggressive, and restless. She showed disruptive behavior, including screaming in the wards and showing her will to leave the hospital. She was diagnosed with bipolar disorder I, a manic episode, and was admitted to the hospital with her mother's companion. Rapid tranquilizers were given at the start, and then mood stabilizers and antipsychotics were prescribed.
Conclusion: We advocate the idea that caution must be taken in treating depression with citalopram in young populations, even in the absence of a family history of affective illness. |
| format | Article |
| id | doaj-art-bc74bf5389ad4f098fa5bc3d02cda92a |
| institution | DOAJ |
| issn | 2319-5363 2583-4010 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Jaypee Brothers Medical Publisher |
| record_format | Article |
| series | Indian Journal of Private Psychiatry |
| spelling | doaj-art-bc74bf5389ad4f098fa5bc3d02cda92a2025-08-20T03:05:25ZengJaypee Brothers Medical PublisherIndian Journal of Private Psychiatry2319-53632583-40102024-01-01181515410.5005/jp-journals-10067-016016Mania Induced by a Low Dose of Citalopram: A Case ReportJaafar Omer Ahmed0https://orcid.org/0000-0001-5904-3695Koyar Sherko M Salih1Makwan Mohammed Abdulkareem2Jaafar Omer Ahmed, Department of Mental Health, Shahid Hemn Mental Hospital, Sulaymaniyah, Kurdistan Region, Iraq, Phone: +009647501471229Department of Mental Health, Shahid Hemn Mental Hospital, Sulaymaniyah, Kurdistan Region, IraqDepartment of Mental Health, Hospital of Treatment Victims of Chemical Weapons, Halabja, IraqBackground: Antidepressant-induced mania is commonly observed in contemporary clinical practice. The problem in patients with unipolar depression has been evident since the introduction of the first antidepressants. Selective serotonin reuptake inhibitors (SSRIs), as new drugs, are one of those drugs that may lead to treatment-induced mania. The risk of inducing mania in bipolar patients with citalopram is comparable to the documented risk with other SSRIs. This case study elucidates the crucial factors for distinguishing key depressive episodes between bipolar and unipolar depression and provides recommendations regarding the use of antidepressants in high-risk patients. Case presentation: A 24-year-old Kurdish woman developed mania after self-administering a low dose of Citalopram for depression. Diana Azad (DA) is a 24-year-old single female. She was referred to the Mental Health Treatment Center by the police under a judicial order for psychiatric assessment and treatment. DA was irritable, aggressive, and restless. She showed disruptive behavior, including screaming in the wards and showing her will to leave the hospital. She was diagnosed with bipolar disorder I, a manic episode, and was admitted to the hospital with her mother's companion. Rapid tranquilizers were given at the start, and then mood stabilizers and antipsychotics were prescribed. Conclusion: We advocate the idea that caution must be taken in treating depression with citalopram in young populations, even in the absence of a family history of affective illness.https://www.ijiapp.com/doi/IJPP/pdf/10.5005/jp-journals-10067-0160antidepressant-induced maniabipolar depressioncase reportcitalopramselective serotonin uptake inhibitors |
| spellingShingle | Jaafar Omer Ahmed Koyar Sherko M Salih Makwan Mohammed Abdulkareem Mania Induced by a Low Dose of Citalopram: A Case Report Indian Journal of Private Psychiatry antidepressant-induced mania bipolar depression case report citalopram selective serotonin uptake inhibitors |
| title | Mania Induced by a Low Dose of Citalopram: A Case Report |
| title_full | Mania Induced by a Low Dose of Citalopram: A Case Report |
| title_fullStr | Mania Induced by a Low Dose of Citalopram: A Case Report |
| title_full_unstemmed | Mania Induced by a Low Dose of Citalopram: A Case Report |
| title_short | Mania Induced by a Low Dose of Citalopram: A Case Report |
| title_sort | mania induced by a low dose of citalopram a case report |
| topic | antidepressant-induced mania bipolar depression case report citalopram selective serotonin uptake inhibitors |
| url | https://www.ijiapp.com/doi/IJPP/pdf/10.5005/jp-journals-10067-0160 |
| work_keys_str_mv | AT jaafaromerahmed maniainducedbyalowdoseofcitalopramacasereport AT koyarsherkomsalih maniainducedbyalowdoseofcitalopramacasereport AT makwanmohammedabdulkareem maniainducedbyalowdoseofcitalopramacasereport |