Non-invasive MRI of blood-cerebrospinal fluid-barrier function in a mouse model of Alzheimer’s disease: a potential biomarker of early pathology

Non-invasive MRI of blood-cerebrospinal fluid-barrier function in a mouse model of Alzheimer’s disease: a potential biomarker of early pathology

Abstract Background Choroid plexus (CP) or blood-cerebrospinal fluid-barrier (BCSFB) is a unique functional tissue which lines the brain’s fluid-filled ventricles, with a crucial role in CSF production and clearance. BCSFB dysfunction is thought to contribute to toxic protein build-up in neurodegene...

Full description

Saved in:
Bibliographic Details
Main Authors: Charith Perera, Renata Cruz, Noam Shemesh, Tânia Carvalho, David L. Thomas, Jack Wells, Andrada Ianuș
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Fluids and Barriers of the CNS
Subjects:
Alzheimer’s disease
Choroid plexus
Blood CSF barrier
Brain perfusion
Arterial spin labelling MRI
3xTg mouse model
Online Access:https://doi.org/10.1186/s12987-024-00597-7
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items