Lipidomics and whole-genome sequencing identify lipid profiles in fermented golden pompano (Trachinotus ovatus) inoculated with Bacillus subtilis: influence of indigenous strains on lipid changes

Inoculated fermentation enables rapid fermentation of aquatic products. No studies have been conducted on the lipid profiles of inoculated fermented golden pompano (Trachinotus ovatus). In this study, a lipase-producing Bacillus subtilis with salt tolerance was screened from traditionally fermented...

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Main Authors: Yanyan Wu, Huifang Wang, Huan Xiang, Di Wang, Chunsheng Li, Shengjun Chen, Yongqiang Zhao, Yueqi Wang
Format: Article
Language:English
Published: Tsinghua University Press 2025-06-01
Series:Food Science and Human Wellness
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Online Access:https://www.sciopen.com/article/10.26599/FSHW.2024.9250141
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author Yanyan Wu
Huifang Wang
Huan Xiang
Di Wang
Chunsheng Li
Shengjun Chen
Yongqiang Zhao
Yueqi Wang
author_facet Yanyan Wu
Huifang Wang
Huan Xiang
Di Wang
Chunsheng Li
Shengjun Chen
Yongqiang Zhao
Yueqi Wang
author_sort Yanyan Wu
collection DOAJ
description Inoculated fermentation enables rapid fermentation of aquatic products. No studies have been conducted on the lipid profiles of inoculated fermented golden pompano (Trachinotus ovatus). In this study, a lipase-producing Bacillus subtilis with salt tolerance was screened from traditionally fermented golden pompano (TF) and used as a starter culture. Whole-genome sequencing analysis revealed it carries 4 clustered regularly interspaced short vpalindromic repeats structures and 2 genes encoding triacylglycerol lipase. Untargeted lipidomics identified lipid molecules (833) in 6 major classes from B. subtilis SCSMX-2 fermented golden pompano (IF). A total of 28 lipid molecules were upregulated in IF, including phosphatidylcholines (PCs), triacylglycerols (TAGs), and lysophosphatidylcholine. B. subtilis supplementation enhanced the production of polyenyl PCs and medium- and long-chain TAGs. The IF rich in linoleic, docosahexaenoic acids (DHA), and eicosapentaenoic acid were primarily distributed in the sn-2 position of DHA, PC and phosphatidylethanolamine. This research revealed the lipid profiles of IF, providing theoretical basis for the application of B. subtilis in the fermented fish industry.
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institution Kabale University
issn 2097-0765
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language English
publishDate 2025-06-01
publisher Tsinghua University Press
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spelling doaj-art-bc6b5a0e3bd3411ab7d51c4639d8a6a82025-08-20T03:41:14ZengTsinghua University PressFood Science and Human Wellness2097-07652213-45302025-06-01146925014110.26599/FSHW.2024.9250141Lipidomics and whole-genome sequencing identify lipid profiles in fermented golden pompano (Trachinotus ovatus) inoculated with Bacillus subtilis: influence of indigenous strains on lipid changesYanyan Wu0Huifang Wang1Huan Xiang2Di Wang3Chunsheng Li4Shengjun Chen5Yongqiang Zhao6Yueqi Wang7Key Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural Affairs, National R&D Center for Aquatic Product Processing, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, ChinaKey Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural Affairs, National R&D Center for Aquatic Product Processing, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, ChinaKey Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural Affairs, National R&D Center for Aquatic Product Processing, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, ChinaKey Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural Affairs, National R&D Center for Aquatic Product Processing, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, ChinaKey Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural Affairs, National R&D Center for Aquatic Product Processing, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, ChinaKey Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural Affairs, National R&D Center for Aquatic Product Processing, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, ChinaKey Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural Affairs, National R&D Center for Aquatic Product Processing, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, ChinaKey Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural Affairs, National R&D Center for Aquatic Product Processing, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, ChinaInoculated fermentation enables rapid fermentation of aquatic products. No studies have been conducted on the lipid profiles of inoculated fermented golden pompano (Trachinotus ovatus). In this study, a lipase-producing Bacillus subtilis with salt tolerance was screened from traditionally fermented golden pompano (TF) and used as a starter culture. Whole-genome sequencing analysis revealed it carries 4 clustered regularly interspaced short vpalindromic repeats structures and 2 genes encoding triacylglycerol lipase. Untargeted lipidomics identified lipid molecules (833) in 6 major classes from B. subtilis SCSMX-2 fermented golden pompano (IF). A total of 28 lipid molecules were upregulated in IF, including phosphatidylcholines (PCs), triacylglycerols (TAGs), and lysophosphatidylcholine. B. subtilis supplementation enhanced the production of polyenyl PCs and medium- and long-chain TAGs. The IF rich in linoleic, docosahexaenoic acids (DHA), and eicosapentaenoic acid were primarily distributed in the sn-2 position of DHA, PC and phosphatidylethanolamine. This research revealed the lipid profiles of IF, providing theoretical basis for the application of B. subtilis in the fermented fish industry.https://www.sciopen.com/article/10.26599/FSHW.2024.9250141untargeted lipidomicsgolden pompanofermentationlipasewhole genome
spellingShingle Yanyan Wu
Huifang Wang
Huan Xiang
Di Wang
Chunsheng Li
Shengjun Chen
Yongqiang Zhao
Yueqi Wang
Lipidomics and whole-genome sequencing identify lipid profiles in fermented golden pompano (Trachinotus ovatus) inoculated with Bacillus subtilis: influence of indigenous strains on lipid changes
Food Science and Human Wellness
untargeted lipidomics
golden pompano
fermentation
lipase
whole genome
title Lipidomics and whole-genome sequencing identify lipid profiles in fermented golden pompano (Trachinotus ovatus) inoculated with Bacillus subtilis: influence of indigenous strains on lipid changes
title_full Lipidomics and whole-genome sequencing identify lipid profiles in fermented golden pompano (Trachinotus ovatus) inoculated with Bacillus subtilis: influence of indigenous strains on lipid changes
title_fullStr Lipidomics and whole-genome sequencing identify lipid profiles in fermented golden pompano (Trachinotus ovatus) inoculated with Bacillus subtilis: influence of indigenous strains on lipid changes
title_full_unstemmed Lipidomics and whole-genome sequencing identify lipid profiles in fermented golden pompano (Trachinotus ovatus) inoculated with Bacillus subtilis: influence of indigenous strains on lipid changes
title_short Lipidomics and whole-genome sequencing identify lipid profiles in fermented golden pompano (Trachinotus ovatus) inoculated with Bacillus subtilis: influence of indigenous strains on lipid changes
title_sort lipidomics and whole genome sequencing identify lipid profiles in fermented golden pompano trachinotus ovatus inoculated with bacillus subtilis influence of indigenous strains on lipid changes
topic untargeted lipidomics
golden pompano
fermentation
lipase
whole genome
url https://www.sciopen.com/article/10.26599/FSHW.2024.9250141
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AT yueqiwang lipidomicsandwholegenomesequencingidentifylipidprofilesinfermentedgoldenpompanotrachinotusovatusinoculatedwithbacillussubtilisinfluenceofindigenousstrainsonlipidchanges