Common themes in architecture and interactions of prokaryotic PolB2 and Pol V mutasomes inferred from in silico studies

Translesion DNA synthesis (TLS) is typically performed by inherently error-prone Y-family DNA polymerases. Extensively studied Escherichia coli Pol V mutasome, composed of UmuC, an UmuD′ dimer and RecA is an example of a multimeric Y-family TLS polymerase. Less commonly TLS is performed by DNA polym...

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Bibliographic Details
Main Authors: Kęstutis Timinskas, Albertas Timinskas, Česlovas Venclovas
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Computational and Structural Biotechnology Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S2001037025000108
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