Common themes in architecture and interactions of prokaryotic PolB2 and Pol V mutasomes inferred from in silico studies
Translesion DNA synthesis (TLS) is typically performed by inherently error-prone Y-family DNA polymerases. Extensively studied Escherichia coli Pol V mutasome, composed of UmuC, an UmuD′ dimer and RecA is an example of a multimeric Y-family TLS polymerase. Less commonly TLS is performed by DNA polym...
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Main Authors: | Kęstutis Timinskas, Albertas Timinskas, Česlovas Venclovas |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-01-01
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Series: | Computational and Structural Biotechnology Journal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037025000108 |
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