Periodontitis promotes tumor growth and immune evasion via PD-1/PD-L1

Periodontitis promotes tumor growth and immune evasion via PD-1/PD-L1

Abstract Background Our study investigated the role of experimental periodontitis on tumor growth, local and systemic immunosuppressive status, and programmed death receptor 1 (PD-1) / programmed death ligand 1 (PD-L1) expression in oral squamous cell carcinoma (OSCC) and prostate cancer. Methods Mo...

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Bibliographic Details
Main Authors: Suli Wang, Fujiao Nie, Qiuyue Yin, Haoyang Tian, Pizhang Gong, Jinhong Ju, Jiayi Liu, Pishan Yang, Chengzhe Yang
Format: Article
Language:English
Published: Springer 2024-11-01
Series:Cancer Immunology, Immunotherapy
Subjects:
Periodontitis
Oral cancer
Prostate cancer
Tumor immunosuppression microenvironment
PD-1/PD-L1
Online Access:https://doi.org/10.1007/s00262-024-03865-5
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