MMP12 deficiency attenuates menthol e-cigarette plus house dust-mite effects on pulmonary iron homeostasis and oxidative stress

MMP12 deficiency attenuates menthol e-cigarette plus house dust-mite effects on pulmonary iron homeostasis and oxidative stress

Abstract Background Little is known regarding the pulmonary effects induced by the inhalation of menthol-flavored e-cigarette aerosols on asthma exacerbation, despite the popularity of these devices and flavors among youth and young adults. In the lungs, matrix metalloproteinase 12 (MMP12) expressed...

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Bibliographic Details
Main Authors: Rakeysha I. Pinkston, Matthew Schexnayder, Zakia Perveen, Ingeborg M. Langohr, Tomislav Jelesijevic, Arthur L. Penn, Alexandra Noël
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Respiratory Research
Subjects:
Electronic nicotine delivery system (ENDS)
Electronic-cigarette
Pulmonary iron homeostasis
Asthma
MMP12
Online Access:https://doi.org/10.1186/s12931-025-03213-w
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