The Lyn/RUVBL1 Complex Promotes Colorectal Cancer Liver Metastasis by Regulating Arachidonic Acid Metabolism Through Chromatin Remodeling

The Lyn/RUVBL1 Complex Promotes Colorectal Cancer Liver Metastasis by Regulating Arachidonic Acid Metabolism Through Chromatin Remodeling

Abstract Liver metastasis is a common cause of death in colorectal cancer (CRC) patients, but epigenetic remodeling and metabolic reprogramming for CRC liver metastasis remain unclear. The study revealed that the Lyn/RUVBL1 complex is highly expressed in CRC and is closely correlated with liver meta...

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Bibliographic Details
Main Authors:	Zhenyu Zhang, Yina Gao, Yuanyuan Qian, Bowen Wei, Kexin Jiang, Zhiwei Sun, Feifan Zhang, Mingming Yang, Salem Baldi, Xiaoqi Yu, Yunfei Zuo, Shuangyi Ren
Format:	Article
Language:	English
Published:	Wiley 2025-02-01
Series:	Advanced Science
Subjects:	arachidonic acid metabolism chromatin remodeling colorectal cancer liver metastasis Lyn RUVBL1
Online Access:	https://doi.org/10.1002/advs.202406562
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