The Lyn/RUVBL1 Complex Promotes Colorectal Cancer Liver Metastasis by Regulating Arachidonic Acid Metabolism Through Chromatin Remodeling

The Lyn/RUVBL1 Complex Promotes Colorectal Cancer Liver Metastasis by Regulating Arachidonic Acid Metabolism Through Chromatin Remodeling

Abstract Liver metastasis is a common cause of death in colorectal cancer (CRC) patients, but epigenetic remodeling and metabolic reprogramming for CRC liver metastasis remain unclear. The study revealed that the Lyn/RUVBL1 complex is highly expressed in CRC and is closely correlated with liver meta...

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Bibliographic Details
Main Authors: Zhenyu Zhang, Yina Gao, Yuanyuan Qian, Bowen Wei, Kexin Jiang, Zhiwei Sun, Feifan Zhang, Mingming Yang, Salem Baldi, Xiaoqi Yu, Yunfei Zuo, Shuangyi Ren
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Advanced Science
Subjects:
arachidonic acid metabolism
chromatin remodeling
colorectal cancer liver metastasis
Lyn
RUVBL1
Online Access:https://doi.org/10.1002/advs.202406562
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https://doi.org/10.1002/advs.202406562

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