Treatment of pro-B acute lymphoblastic leukemia and severe plaque psoriasis with anti-CD19 CAR T cells: a case report

Treatment of pro-B acute lymphoblastic leukemia and severe plaque psoriasis with anti-CD19 CAR T cells: a case report

We report on a rare case of adult pro-B acute lymphoblastic leukemia (pro-B ALL) accompanied with severe refractory plaque psoriasis treated using autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. An 18-year-old man with a known history of mild plaque psoriasis for 1 year was diag...

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Bibliographic Details
Main Authors: Ao Zhang, Guangji Zhang, Huihui Yang, Bengfa Gong, Shouyun Li, Na Wei, Hui Xue, Hui Wei, Jianxiang Wang, Shaowei Qiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
Subjects:
pro-B ALL
psoriasis
CD19 CAR T cells
B cell
therapeutic targets
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1529745/full
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