Cognitive Function Characteristics of Parkinson’s Disease with Sleep Disorders
Objective. The aim of this study was to investigate the cognitive function characteristics of Parkinson’s disease (PD) with sleep disorders. Methods. Consecutive patients with PD (n=96), patients with primary sleep disorders (n=76), and healthy control subjects (n=66) were assessed. The patients wit...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Parkinson's Disease |
| Online Access: | http://dx.doi.org/10.1155/2017/4267353 |
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| _version_ | 1832559855820341248 |
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| author | Jing Huang Wenyan Zhuo Yuhu Zhang Hongchun Sun Huan Chen Peipei Zhu Xiaobo Pan Jianhao Yang Lijuan Wang |
| author_facet | Jing Huang Wenyan Zhuo Yuhu Zhang Hongchun Sun Huan Chen Peipei Zhu Xiaobo Pan Jianhao Yang Lijuan Wang |
| author_sort | Jing Huang |
| collection | DOAJ |
| description | Objective. The aim of this study was to investigate the cognitive function characteristics of Parkinson’s disease (PD) with sleep disorders. Methods. Consecutive patients with PD (n=96), patients with primary sleep disorders (n=76), and healthy control subjects (n=66) were assessed. The patients with PD were classified into sleep disorder (PD-SD) and non-sleep disorder (PD-NSD) groups. Results. Among 96 patients with PD, 69 were diagnosed with a sleep disorder. There were 38 sleep disorder cases, 31 RBD cases, and 27 NSD cases. On the Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), and MoCA subtests, patients in the PD-SD, primary sleep disorder, and PD-NSD groups exhibited lower scores than those in the control group. Moreover, the PD-SD patients exhibited more significant cognitive impairment than was observed in the primary sleep disorder patients. In the PD-SD subgroup, the attention scores on the MoCA and on MoCA subtests were lower in the PD with RBD group than in the PD with insomnia group. Conclusion. PD with sleep disorders may exacerbate cognitive dysfunction in patients. PD associated with different types of sleep disorders differentially affects cognitive functions, and patients with PD with RBD exhibited poorer cognitive function than was seen in patients with PD with insomnia. |
| format | Article |
| id | doaj-art-bc373ae75d69458cb2c33c4b0c65d93d |
| institution | Kabale University |
| issn | 2090-8083 2042-0080 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Parkinson's Disease |
| spelling | doaj-art-bc373ae75d69458cb2c33c4b0c65d93d2025-02-03T01:29:10ZengWileyParkinson's Disease2090-80832042-00802017-01-01201710.1155/2017/42673534267353Cognitive Function Characteristics of Parkinson’s Disease with Sleep DisordersJing Huang0Wenyan Zhuo1Yuhu Zhang2Hongchun Sun3Huan Chen4Peipei Zhu5Xiaobo Pan6Jianhao Yang7Lijuan Wang8Department of Neurology, Zhuhai People’s Hospital, Zhuhai 519000, ChinaDepartment of Neurology, Zhuhai People’s Hospital, Zhuhai 519000, ChinaDepartment of Neurology, Guangdong Neuroscience Institute, Guangdong General Hospital and Guangdong Academy of Medical Sciences, Guangzhou 510080, ChinaDepartment of Neurology, Zhuhai People’s Hospital, Zhuhai 519000, ChinaDepartment of Neurology, Zhuhai People’s Hospital, Zhuhai 519000, ChinaDepartment of Neurology, Zhuhai People’s Hospital, Zhuhai 519000, ChinaDepartment of Neurology, Zhuhai People’s Hospital, Zhuhai 519000, ChinaDepartment of Neurology, Zhuhai People’s Hospital, Zhuhai 519000, ChinaDepartment of Neurology, Guangdong Neuroscience Institute, Guangdong General Hospital and Guangdong Academy of Medical Sciences, Guangzhou 510080, ChinaObjective. The aim of this study was to investigate the cognitive function characteristics of Parkinson’s disease (PD) with sleep disorders. Methods. Consecutive patients with PD (n=96), patients with primary sleep disorders (n=76), and healthy control subjects (n=66) were assessed. The patients with PD were classified into sleep disorder (PD-SD) and non-sleep disorder (PD-NSD) groups. Results. Among 96 patients with PD, 69 were diagnosed with a sleep disorder. There were 38 sleep disorder cases, 31 RBD cases, and 27 NSD cases. On the Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), and MoCA subtests, patients in the PD-SD, primary sleep disorder, and PD-NSD groups exhibited lower scores than those in the control group. Moreover, the PD-SD patients exhibited more significant cognitive impairment than was observed in the primary sleep disorder patients. In the PD-SD subgroup, the attention scores on the MoCA and on MoCA subtests were lower in the PD with RBD group than in the PD with insomnia group. Conclusion. PD with sleep disorders may exacerbate cognitive dysfunction in patients. PD associated with different types of sleep disorders differentially affects cognitive functions, and patients with PD with RBD exhibited poorer cognitive function than was seen in patients with PD with insomnia.http://dx.doi.org/10.1155/2017/4267353 |
| spellingShingle | Jing Huang Wenyan Zhuo Yuhu Zhang Hongchun Sun Huan Chen Peipei Zhu Xiaobo Pan Jianhao Yang Lijuan Wang Cognitive Function Characteristics of Parkinson’s Disease with Sleep Disorders Parkinson's Disease |
| title | Cognitive Function Characteristics of Parkinson’s Disease with Sleep Disorders |
| title_full | Cognitive Function Characteristics of Parkinson’s Disease with Sleep Disorders |
| title_fullStr | Cognitive Function Characteristics of Parkinson’s Disease with Sleep Disorders |
| title_full_unstemmed | Cognitive Function Characteristics of Parkinson’s Disease with Sleep Disorders |
| title_short | Cognitive Function Characteristics of Parkinson’s Disease with Sleep Disorders |
| title_sort | cognitive function characteristics of parkinson s disease with sleep disorders |
| url | http://dx.doi.org/10.1155/2017/4267353 |
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