Synthesis and Analgesic Studies of Some New 2-pyrazolines
A new series of 2-pyrazolines (4a-j) were synthesized by reacting chalcones (3a-j) with phenyl hydrazine in the presence of pyridine and ethanol. All these compounds were characterized by means of their IR, 1H-NMR spectral data and microanalyses. When these compounds were evaluated for analgesic act...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2012/476989 |
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| author | S. Sridhar Y. Rajendraprasad |
| author_facet | S. Sridhar Y. Rajendraprasad |
| author_sort | S. Sridhar |
| collection | DOAJ |
| description | A new series of 2-pyrazolines (4a-j) were synthesized by reacting chalcones (3a-j) with phenyl hydrazine in the presence of pyridine and ethanol. All these compounds were characterized by means of their IR, 1H-NMR spectral data and microanalyses. When these compounds were evaluated for analgesic activity, some of them were found to possess significant activity, when compared to standard drugs. |
| format | Article |
| id | doaj-art-bc23bc20ed304f1594949740f7e6fef2 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-bc23bc20ed304f1594949740f7e6fef22025-02-03T05:43:41ZengWileyE-Journal of Chemistry0973-49452090-98102012-01-01941810181510.1155/2012/476989Synthesis and Analgesic Studies of Some New 2-pyrazolinesS. Sridhar0Y. Rajendraprasad1Department of Pharmaceutical Chemistry, Malla Reddy College of Pharmacy, Secunderabad, IndiaUniversity College of Pharmaceutical Sciences, Andhra University, Vishakapatanam, IndiaA new series of 2-pyrazolines (4a-j) were synthesized by reacting chalcones (3a-j) with phenyl hydrazine in the presence of pyridine and ethanol. All these compounds were characterized by means of their IR, 1H-NMR spectral data and microanalyses. When these compounds were evaluated for analgesic activity, some of them were found to possess significant activity, when compared to standard drugs.http://dx.doi.org/10.1155/2012/476989 |
| spellingShingle | S. Sridhar Y. Rajendraprasad Synthesis and Analgesic Studies of Some New 2-pyrazolines E-Journal of Chemistry |
| title | Synthesis and Analgesic Studies of Some New 2-pyrazolines |
| title_full | Synthesis and Analgesic Studies of Some New 2-pyrazolines |
| title_fullStr | Synthesis and Analgesic Studies of Some New 2-pyrazolines |
| title_full_unstemmed | Synthesis and Analgesic Studies of Some New 2-pyrazolines |
| title_short | Synthesis and Analgesic Studies of Some New 2-pyrazolines |
| title_sort | synthesis and analgesic studies of some new 2 pyrazolines |
| url | http://dx.doi.org/10.1155/2012/476989 |
| work_keys_str_mv | AT ssridhar synthesisandanalgesicstudiesofsomenew2pyrazolines AT yrajendraprasad synthesisandanalgesicstudiesofsomenew2pyrazolines |