TUBB2B regulates epithelial-mesenchymal transition via interaction with Vimentin to promote glioma migration and invasion

TUBB2B regulates epithelial-mesenchymal transition via interaction with Vimentin to promote glioma migration and invasion

Abstract Background Epithelial-mesenchymal transition (EMT) plays a crucial role in the migration and invasion capabilities of glioblastoma (GBM) cells. Several studies have established tubulin as a significant regulator of the EMT process. Tubulin beta 2B class IIb (TUBB2B), a critical component of...

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Bibliographic Details
Main Authors: Junxi Li, Zhengjun Zhou, Junrong Zhang, Ming Wang, Xingzhao Luan, Mingkuan Zhao, Geng Jiang, Guiyuan Wang, Shenjie Li, Wei Xiang, Ligang Chen, Jie Zhou
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cancer Cell International
Subjects:
TUBB2B
Epithelial-mesenchymal transition
Glioblastoma
Vimentin
Online Access:https://doi.org/10.1186/s12935-024-03618-5
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