Pathological & cytogenetic effects of different doses of Cobelt-60 in induced chromosomal aberrations and sister-chromatid exchanges – in rats
The present study was done in different period to study the pathological effects of different doses of Cobalt – 60 radiation which represent an example of gamma rays in white rats by study the pathological & cytogentic changes. Two groups of rats exposure ,first : C0 50 second C- 150 gray for (...
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| Format: | Article |
| Language: | English |
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University of Baghdad, College of Veterinary Medicine
2005-12-01
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| Series: | The Iraqi Journal of Veterinary Medicine |
| Online Access: | https://www.jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/1973 |
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| author | Bushra. I.Al-Kaisie |
| author_facet | Bushra. I.Al-Kaisie |
| author_sort | Bushra. I.Al-Kaisie |
| collection | DOAJ |
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The present study was done in different period to study the pathological effects of different doses of Cobalt – 60 radiation which represent an example of gamma rays in white rats by study the pathological & cytogentic changes. Two groups of rats exposure ,first : C0 50 second C- 150 gray for (0,30,45,90)days and the 3rd group control .The results show significant increased P<0.01 in micronuclei with high dose (C-150). Chromosomal aberration and SCE showed significant P<0.01 increased mostly in C-150 at (45 7 90)days of exposure with frequency of breaks ,dicentric , acentric and ring shape with significant reduction in mitotic index (MI)and replicative (RI) index. Pathological changes revealed that increased and enlargement with granulomatous lesion of kidney , :Liver , lungs of (C-50) and (C-150)groups. Histopathological lesion showed development of adenocarcinoma in lung , liver with granulomatous lesion in
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| format | Article |
| id | doaj-art-bc147094de09454893059d53aa171936 |
| institution | Kabale University |
| issn | 1609-5693 2410-7409 |
| language | English |
| publishDate | 2005-12-01 |
| publisher | University of Baghdad, College of Veterinary Medicine |
| record_format | Article |
| series | The Iraqi Journal of Veterinary Medicine |
| spelling | doaj-art-bc147094de09454893059d53aa1719362025-08-20T03:46:46ZengUniversity of Baghdad, College of Veterinary MedicineThe Iraqi Journal of Veterinary Medicine1609-56932410-74092005-12-0129210.30539/gggyk294Pathological & cytogenetic effects of different doses of Cobelt-60 in induced chromosomal aberrations and sister-chromatid exchanges – in ratsBushra. I.Al-Kaisie0Depatment of Pathology –Vet. College Baghdad University The present study was done in different period to study the pathological effects of different doses of Cobalt – 60 radiation which represent an example of gamma rays in white rats by study the pathological & cytogentic changes. Two groups of rats exposure ,first : C0 50 second C- 150 gray for (0,30,45,90)days and the 3rd group control .The results show significant increased P<0.01 in micronuclei with high dose (C-150). Chromosomal aberration and SCE showed significant P<0.01 increased mostly in C-150 at (45 7 90)days of exposure with frequency of breaks ,dicentric , acentric and ring shape with significant reduction in mitotic index (MI)and replicative (RI) index. Pathological changes revealed that increased and enlargement with granulomatous lesion of kidney , :Liver , lungs of (C-50) and (C-150)groups. Histopathological lesion showed development of adenocarcinoma in lung , liver with granulomatous lesion in https://www.jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/1973 |
| spellingShingle | Bushra. I.Al-Kaisie Pathological & cytogenetic effects of different doses of Cobelt-60 in induced chromosomal aberrations and sister-chromatid exchanges – in rats The Iraqi Journal of Veterinary Medicine |
| title | Pathological & cytogenetic effects of different doses of Cobelt-60 in induced chromosomal aberrations and sister-chromatid exchanges – in rats |
| title_full | Pathological & cytogenetic effects of different doses of Cobelt-60 in induced chromosomal aberrations and sister-chromatid exchanges – in rats |
| title_fullStr | Pathological & cytogenetic effects of different doses of Cobelt-60 in induced chromosomal aberrations and sister-chromatid exchanges – in rats |
| title_full_unstemmed | Pathological & cytogenetic effects of different doses of Cobelt-60 in induced chromosomal aberrations and sister-chromatid exchanges – in rats |
| title_short | Pathological & cytogenetic effects of different doses of Cobelt-60 in induced chromosomal aberrations and sister-chromatid exchanges – in rats |
| title_sort | pathological cytogenetic effects of different doses of cobelt 60 in induced chromosomal aberrations and sister chromatid exchanges in rats |
| url | https://www.jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/1973 |
| work_keys_str_mv | AT bushraialkaisie pathologicalcytogeneticeffectsofdifferentdosesofcobelt60ininducedchromosomalaberrationsandsisterchromatidexchangesinrats |