Evaluating linum usitatissimum seeds extract as potential alternative biochemical and therapeutic agent against induced coccidiosis in broiler chicken

Coccidiosis is a significant disease of poultry and is usually treated using various synthetic anticoccidial drugs. However, the effectiveness of this approach has been compromised due to drug resistance. Medicinal plants are being considered as potential alternatives to these drugs. As part of ongo...

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Main Authors: Kashif HUSSAIN, Asghar ABBAS, Atif REHMAN, Muhammad Umair WAQAS, Baseer AHMAD, Muhammad Adnan Sabir MUGHAL, Rao Zahid ABBAS, Muhammad Arfan ZAMAN, Junaid Ali KHAN, Muhammad Asif RAZA
Format: Article
Language:English
Published: Kafkas University, Faculty of Veterinary Medicine 2024-10-01
Series:Kafkas Universitesi Veteriner Fakültesi Dergisi
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Online Access:https://vetdergikafkas.org/pdf.php?id=3144
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author Kashif HUSSAIN
Asghar ABBAS
Atif REHMAN
Muhammad Umair WAQAS
Baseer AHMAD
Muhammad Adnan Sabir MUGHAL
Rao Zahid ABBAS
Muhammad Arfan ZAMAN
Junaid Ali KHAN
Muhammad Asif RAZA
author_facet Kashif HUSSAIN
Asghar ABBAS
Atif REHMAN
Muhammad Umair WAQAS
Baseer AHMAD
Muhammad Adnan Sabir MUGHAL
Rao Zahid ABBAS
Muhammad Arfan ZAMAN
Junaid Ali KHAN
Muhammad Asif RAZA
author_sort Kashif HUSSAIN
collection DOAJ
description Coccidiosis is a significant disease of poultry and is usually treated using various synthetic anticoccidial drugs. However, the effectiveness of this approach has been compromised due to drug resistance. Medicinal plants are being considered as potential alternatives to these drugs. As part of ongoing research, an investigation was conducted to assess the anticoccidial potential of Linum usitatissimum seed extract (LUE) and its impact on hematological parameters in broiler chickens with experimental coccidiosis. A total of 108 broiler chicks were divided into six groups. The chicks in Groups I, II, and III were given plant extract at three different concentrations: 4%, 5%, and 6%, respectively, at one week of age. Group IV was the positive control - these chickens were treated with toltrazuril. Group V served as the negative control, meaning they were infected but not given any medication. Group VI was the normal control group. All groups, except Group VI, were orally infected with 60,000 sporulated oocysts when they were 18 days old. After 7 days of giving orally infection, six birds from each group were euthanized so that we could examine their feed conversion ratio (FCR), oocyst score, lesion score, fecal score, serum chemistry and hematology. The results showed that the L. usitatissimum extract exhibited anticoccidial activity. It improved the FCR and reduced lesion, oocyst, fecal scores and blood and serum chemistry.
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spelling doaj-art-bbf2eb57f7be4189b8564d7a15f65f532025-08-20T01:59:20ZengKafkas University, Faculty of Veterinary MedicineKafkas Universitesi Veteriner Fakültesi Dergisi1309-22512024-10-0130680380810.9775/kvfd.2024.326183144Evaluating linum usitatissimum seeds extract as potential alternative biochemical and therapeutic agent against induced coccidiosis in broiler chickenKashif HUSSAIN0Asghar ABBAS1Atif REHMAN2Muhammad Umair WAQAS3Baseer AHMAD4Muhammad Adnan Sabir MUGHAL5Rao Zahid ABBAS6Muhammad Arfan ZAMAN7Junaid Ali KHAN8Muhammad Asif RAZA9Department of Pathobiology Pathobiology, Faculty of Veterinary and Animal Sciences, Muhammad Nawaz Sharif University of Agriculture, 66000, Multan, PAKISTANDepartment of Pathobiology Pathobiology, Faculty of Veterinary and Animal Sciences, Muhammad Nawaz Sharif University of Agriculture, 66000, Multan, PAKISTANDepartment of Pathobiology Pathobiology, Faculty of Veterinary and Animal Sciences, Muhammad Nawaz Sharif University of Agriculture, 66000, Multan, PAKISTANDepartment of Pathobiology Pathobiology, Faculty of Veterinary and Animal Sciences, Muhammad Nawaz Sharif University of Agriculture, 66000, Multan, PAKISTANDepartment of Pathobiology Pathobiology, Faculty of Veterinary and Animal Sciences, Muhammad Nawaz Sharif University of Agriculture, 66000, Multan, PAKISTANDepartment of Pathobiology Pathobiology, Faculty of Veterinary and Animal Sciences, Muhammad Nawaz Sharif University of Agriculture, 66000, Multan, PAKISTANDepartment of Parasitology, Faculty of Veterinary Sciences, University of Agriculture, 38000, Faisalabad, PAKISTANCollege of Veterinary and Animal Sciences, 35200, Jhang, PAKISTANDepartment of Pathobiology Pathobiology, Faculty of Veterinary and Animal Sciences, Muhammad Nawaz Sharif University of Agriculture, 66000, Multan, PAKISTANDepartment of Pathobiology Pathobiology, Faculty of Veterinary and Animal Sciences, Muhammad Nawaz Sharif University of Agriculture, 66000, Multan, PAKISTANCoccidiosis is a significant disease of poultry and is usually treated using various synthetic anticoccidial drugs. However, the effectiveness of this approach has been compromised due to drug resistance. Medicinal plants are being considered as potential alternatives to these drugs. As part of ongoing research, an investigation was conducted to assess the anticoccidial potential of Linum usitatissimum seed extract (LUE) and its impact on hematological parameters in broiler chickens with experimental coccidiosis. A total of 108 broiler chicks were divided into six groups. The chicks in Groups I, II, and III were given plant extract at three different concentrations: 4%, 5%, and 6%, respectively, at one week of age. Group IV was the positive control - these chickens were treated with toltrazuril. Group V served as the negative control, meaning they were infected but not given any medication. Group VI was the normal control group. All groups, except Group VI, were orally infected with 60,000 sporulated oocysts when they were 18 days old. After 7 days of giving orally infection, six birds from each group were euthanized so that we could examine their feed conversion ratio (FCR), oocyst score, lesion score, fecal score, serum chemistry and hematology. The results showed that the L. usitatissimum extract exhibited anticoccidial activity. It improved the FCR and reduced lesion, oocyst, fecal scores and blood and serum chemistry.https://vetdergikafkas.org/pdf.php?id=3144anticoccidialchickencoccidiosislinum usitatissimum
spellingShingle Kashif HUSSAIN
Asghar ABBAS
Atif REHMAN
Muhammad Umair WAQAS
Baseer AHMAD
Muhammad Adnan Sabir MUGHAL
Rao Zahid ABBAS
Muhammad Arfan ZAMAN
Junaid Ali KHAN
Muhammad Asif RAZA
Evaluating linum usitatissimum seeds extract as potential alternative biochemical and therapeutic agent against induced coccidiosis in broiler chicken
Kafkas Universitesi Veteriner Fakültesi Dergisi
anticoccidial
chicken
coccidiosis
linum usitatissimum
title Evaluating linum usitatissimum seeds extract as potential alternative biochemical and therapeutic agent against induced coccidiosis in broiler chicken
title_full Evaluating linum usitatissimum seeds extract as potential alternative biochemical and therapeutic agent against induced coccidiosis in broiler chicken
title_fullStr Evaluating linum usitatissimum seeds extract as potential alternative biochemical and therapeutic agent against induced coccidiosis in broiler chicken
title_full_unstemmed Evaluating linum usitatissimum seeds extract as potential alternative biochemical and therapeutic agent against induced coccidiosis in broiler chicken
title_short Evaluating linum usitatissimum seeds extract as potential alternative biochemical and therapeutic agent against induced coccidiosis in broiler chicken
title_sort evaluating linum usitatissimum seeds extract as potential alternative biochemical and therapeutic agent against induced coccidiosis in broiler chicken
topic anticoccidial
chicken
coccidiosis
linum usitatissimum
url https://vetdergikafkas.org/pdf.php?id=3144
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