HPLC method development for fampridine using Analytical Quality by Design approach
Offering a systematic and multivariate analysis of the analytical procedure, development and validation of HPLC methods using Quality by Design approach are in the limelight of current research trends. A new, experimental design-aided HPLC method for fampridine was developed and preliminarily valida...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2020-12-01
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| Series: | Acta Pharmaceutica |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/acph-2020-0036 |
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| _version_ | 1832572505051627520 |
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| author | Kovács Béla Boda Francisc Fülöp Ibolya Székely-Szentmiklósi István Kelemen Éva Katalin Kovács-Deák Boglárka Székely-Szentmiklósi Blanka |
| author_facet | Kovács Béla Boda Francisc Fülöp Ibolya Székely-Szentmiklósi István Kelemen Éva Katalin Kovács-Deák Boglárka Székely-Szentmiklósi Blanka |
| author_sort | Kovács Béla |
| collection | DOAJ |
| description | Offering a systematic and multivariate analysis of the analytical procedure, development and validation of HPLC methods using Quality by Design approach are in the limelight of current research trends. A new, experimental design-aided HPLC method for fampridine was developed and preliminarily validated according to current in-force international guidelines for linearity, accuracy, robustness and precision. |
| format | Article |
| id | doaj-art-bbdf4c1bad3f4470874ced43c6e186dc |
| institution | Kabale University |
| issn | 1846-9558 |
| language | English |
| publishDate | 2020-12-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Acta Pharmaceutica |
| spelling | doaj-art-bbdf4c1bad3f4470874ced43c6e186dc2025-02-02T09:44:23ZengSciendoActa Pharmaceutica1846-95582020-12-0170446548210.2478/acph-2020-0036acph-2020-0036HPLC method development for fampridine using Analytical Quality by Design approachKovács Béla0Boda Francisc1Fülöp Ibolya2Székely-Szentmiklósi István3Kelemen Éva Katalin4Kovács-Deák Boglárka5Székely-Szentmiklósi Blanka6Gedeon Richter Romania, 540306Tîrgu Mureș, RomaniaDepartment of General and Inorganic Chemistry, Faculty of Pharmacy, University of Medicine, Pharmacy, Science and Technology of Tîrgu Mureș 540139, Tîrgu Mureș, RomaniaDepartment of Toxicology and Biopharmacy, Faculty of Pharmacy, University of Medicine, Pharmacy, Science and Technology of Tîrgu Mureș 540139, Tîrgu Mureș, RomaniaGedeon Richter Romania, 540306Tîrgu Mureș, RomaniaGedeon Richter Romania, 540306Tîrgu Mureș, RomaniaDepartment of Biochemistry and the Chemistry of Environmental Factors, Faculty of Pharmacy University of Medicine, Pharmacy, Science and Technology of Tîrgu Mureș 540139, Tîrgu Mureș, RomaniaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Medicine, Pharmacy, Science and Technology of Tîrgu Mureș 540139, Tîrgu Mureș, RomaniaOffering a systematic and multivariate analysis of the analytical procedure, development and validation of HPLC methods using Quality by Design approach are in the limelight of current research trends. A new, experimental design-aided HPLC method for fampridine was developed and preliminarily validated according to current in-force international guidelines for linearity, accuracy, robustness and precision.https://doi.org/10.2478/acph-2020-0036analytical quality by designfampridinehplc |
| spellingShingle | Kovács Béla Boda Francisc Fülöp Ibolya Székely-Szentmiklósi István Kelemen Éva Katalin Kovács-Deák Boglárka Székely-Szentmiklósi Blanka HPLC method development for fampridine using Analytical Quality by Design approach Acta Pharmaceutica analytical quality by design fampridine hplc |
| title | HPLC method development for fampridine using Analytical Quality by Design approach |
| title_full | HPLC method development for fampridine using Analytical Quality by Design approach |
| title_fullStr | HPLC method development for fampridine using Analytical Quality by Design approach |
| title_full_unstemmed | HPLC method development for fampridine using Analytical Quality by Design approach |
| title_short | HPLC method development for fampridine using Analytical Quality by Design approach |
| title_sort | hplc method development for fampridine using analytical quality by design approach |
| topic | analytical quality by design fampridine hplc |
| url | https://doi.org/10.2478/acph-2020-0036 |
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