Qingrehuoxue formula enhances anti-PD-1 immunotherapy in NSCLC by remodeling the tumor immune microenvironment via TREM2 signaling

Qingrehuoxue formula enhances anti-PD-1 immunotherapy in NSCLC by remodeling the tumor immune microenvironment via TREM2 signaling

Abstract Objective This study evaluated the anti-cancer effect of the Qingrehuoxue Formula (QRHXF) and explored its synergistic mechanisms with anti-programmed cell death protein 1 (anti-PD-1), focusing on the tumor mircroenvironment (TME) in non-small cell lung cancer (NSCLC). Methods The major com...

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Bibliographic Details
Main Authors: Bin-bin Li, Yi-yang Jiang, Xue Li, Min-min Yu, Qian Meng, Dan-ni Wang, Ji-miao Zang, Fei Xu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Traditional Chinese medicine
NSCLC
TREM2
anti-PD-1
Tumor-associated macrophage
Online Access:https://doi.org/10.1186/s12906-025-05020-8
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