Clostridium perfringens Septicemia and a Bleeding Ulcer of a Jejunal Interposition: A Case Report and Short Review of the Literature
Introduction. We report a case of Clostridium perfringens septicemia in a patient presenting with a bleeding ulcer of a jejunal interposition. Case Presentation. An 81-year-old female patient was acutely admitted to our hospital due to hematemesis and melena. She had a history of metastatic gastroin...
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| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2018/4278904 |
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| author | W. Wild F. Bormann H. Sweiti N. Tamimi D. Pichulek M. Divo P. Dörr M. Schwarzbach |
| author_facet | W. Wild F. Bormann H. Sweiti N. Tamimi D. Pichulek M. Divo P. Dörr M. Schwarzbach |
| author_sort | W. Wild |
| collection | DOAJ |
| description | Introduction. We report a case of Clostridium perfringens septicemia in a patient presenting with a bleeding ulcer of a jejunal interposition. Case Presentation. An 81-year-old female patient was acutely admitted to our hospital due to hematemesis and melena. She had a history of metastatic gastrointestinal stromal tumor, for which she was receiving second line treatment with sunitinib. She had also undergone a Merendino procedure 4 years prior to presentation. The patient underwent emergency gastroscopy, which revealed a bleeding ulcer in the jejunal interposition. Despite initial endoscopic control of the bleeding and transfusion of blood products, the hemoglobin level continued to drop, and the patient was treated for an assumed hemolytic transfusion reaction. The patient died 3 days following admission, and the results of blood cultures later confirmed a Clostridium perfringens septicemia. The postmortem examination revealed a diffuse spread of Clostridium perfringens to multiple organs. Conclusion. This case is a reminder of the importance of considering septicemia, particularly in association with Clostridium perfringens, as a potential cause of hemolysis. It also demonstrates the extent of organ involvement in a case of diffuse clostridial myonecrosis. |
| format | Article |
| id | doaj-art-bbaab260688e4c0898f211649054547b |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
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| series | Case Reports in Medicine |
| spelling | doaj-art-bbaab260688e4c0898f211649054547b2025-02-03T06:00:47ZengWileyCase Reports in Medicine1687-96271687-96352018-01-01201810.1155/2018/42789044278904Clostridium perfringens Septicemia and a Bleeding Ulcer of a Jejunal Interposition: A Case Report and Short Review of the LiteratureW. Wild0F. Bormann1H. Sweiti2N. Tamimi3D. Pichulek4M. Divo5P. Dörr6M. Schwarzbach7Department of General, Visceral, Vascular and Thoracic Surgery, Clinical Center Frankfurt Höchst, Frankfurt, GermanyDepartment of General, Visceral, Vascular and Thoracic Surgery, Clinical Center Frankfurt Höchst, Frankfurt, GermanyDepartment of General, Visceral, Vascular and Thoracic Surgery, Clinical Center Frankfurt Höchst, Frankfurt, GermanyDepartment of Trauma and Orthopedic Surgery, BG Trauma Center, Frankfurt, GermanyDepartment of Anesthesiology and Emergency Medicine, Clinical Center Frankfurt Höchst, Frankfurt, GermanyDepartment of Pathology, Clinical Center Frankfurt Höchst, Frankfurt, GermanyInstitute of Radiology, Clinical Center Frankfurt Höchst, Frankfurt, GermanyDepartment of General, Visceral, Vascular and Thoracic Surgery, Clinical Center Frankfurt Höchst, Frankfurt, GermanyIntroduction. We report a case of Clostridium perfringens septicemia in a patient presenting with a bleeding ulcer of a jejunal interposition. Case Presentation. An 81-year-old female patient was acutely admitted to our hospital due to hematemesis and melena. She had a history of metastatic gastrointestinal stromal tumor, for which she was receiving second line treatment with sunitinib. She had also undergone a Merendino procedure 4 years prior to presentation. The patient underwent emergency gastroscopy, which revealed a bleeding ulcer in the jejunal interposition. Despite initial endoscopic control of the bleeding and transfusion of blood products, the hemoglobin level continued to drop, and the patient was treated for an assumed hemolytic transfusion reaction. The patient died 3 days following admission, and the results of blood cultures later confirmed a Clostridium perfringens septicemia. The postmortem examination revealed a diffuse spread of Clostridium perfringens to multiple organs. Conclusion. This case is a reminder of the importance of considering septicemia, particularly in association with Clostridium perfringens, as a potential cause of hemolysis. It also demonstrates the extent of organ involvement in a case of diffuse clostridial myonecrosis.http://dx.doi.org/10.1155/2018/4278904 |
| spellingShingle | W. Wild F. Bormann H. Sweiti N. Tamimi D. Pichulek M. Divo P. Dörr M. Schwarzbach Clostridium perfringens Septicemia and a Bleeding Ulcer of a Jejunal Interposition: A Case Report and Short Review of the Literature Case Reports in Medicine |
| title | Clostridium perfringens Septicemia and a Bleeding Ulcer of a Jejunal Interposition: A Case Report and Short Review of the Literature |
| title_full | Clostridium perfringens Septicemia and a Bleeding Ulcer of a Jejunal Interposition: A Case Report and Short Review of the Literature |
| title_fullStr | Clostridium perfringens Septicemia and a Bleeding Ulcer of a Jejunal Interposition: A Case Report and Short Review of the Literature |
| title_full_unstemmed | Clostridium perfringens Septicemia and a Bleeding Ulcer of a Jejunal Interposition: A Case Report and Short Review of the Literature |
| title_short | Clostridium perfringens Septicemia and a Bleeding Ulcer of a Jejunal Interposition: A Case Report and Short Review of the Literature |
| title_sort | clostridium perfringens septicemia and a bleeding ulcer of a jejunal interposition a case report and short review of the literature |
| url | http://dx.doi.org/10.1155/2018/4278904 |
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