A novel source of phytochemical and bioactive peptide from fermented mushroom trimming waste extract by Bifidobacterium longum
The extract from agricultural waste, (golden needle mushroom trimmings) was extracted and fermented with B. longum at 37 °C for 0, 24, 48, and 72 h. The chemical changes and phytochemicals were investigated, as well as antioxidant activity during fermentation, and biological activities such as angio...
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| Language: | English |
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Elsevier
2025-06-01
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| Series: | Applied Food Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772502225000241 |
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| author | Napassorn Peasura Pornrat Sinchaipanit Kanokwan Yodin |
| author_facet | Napassorn Peasura Pornrat Sinchaipanit Kanokwan Yodin |
| author_sort | Napassorn Peasura |
| collection | DOAJ |
| description | The extract from agricultural waste, (golden needle mushroom trimmings) was extracted and fermented with B. longum at 37 °C for 0, 24, 48, and 72 h. The chemical changes and phytochemicals were investigated, as well as antioxidant activity during fermentation, and biological activities such as angiotensin-converting enzyme (ACE) inhibition were investigated. The results found that the growth of B. longum was increased during 0–24 h, while viability declined after 24 h. The greatest concentrations of phenolic compounds and flavonoids were observed at 709.81 and 42.07 mg/mL, respectively. The antioxidant activity levels measured using the 2,2-diphenyl-1-picrylhydrazyl (DPPH•) and 2,2′ -azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS•+) assays were 42.65 % and 45.24 %, respectively. The biological activity, particularly ACE inhibition, was assessed in vitro and was correlated with blood pressure regulation. The fermented mushroom trimming extract had a maximum ACE inhibition value of 9.91 % and a half-maximal inhibitory concentration (IC50) value of 2,134.08 mg/L, making it more effective than the control group with an IC50 value of 2,482.36 mg/L. |
| format | Article |
| id | doaj-art-bba97783f7cf425e9dc9b6b98a29de22 |
| institution | Kabale University |
| issn | 2772-5022 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Applied Food Research |
| spelling | doaj-art-bba97783f7cf425e9dc9b6b98a29de222025-01-22T05:44:23ZengElsevierApplied Food Research2772-50222025-06-0151100714A novel source of phytochemical and bioactive peptide from fermented mushroom trimming waste extract by Bifidobacterium longumNapassorn Peasura0Pornrat Sinchaipanit1Kanokwan Yodin2Institute of Food Research and Product Development, Kasetsart University. 50 Ngamwongwan Road, Lat Yao, Chatuchak, Bangkok 10903, Thailand; Corresponding author.Institute of Nutrition, Mahidol University. 999 Phutthamonthon 4 Rd., Salaya, Phutthamonthon, Nakhon Pathom 73170, ThailandInstitute of Food Research and Product Development, Kasetsart University. 50 Ngamwongwan Road, Lat Yao, Chatuchak, Bangkok 10903, ThailandThe extract from agricultural waste, (golden needle mushroom trimmings) was extracted and fermented with B. longum at 37 °C for 0, 24, 48, and 72 h. The chemical changes and phytochemicals were investigated, as well as antioxidant activity during fermentation, and biological activities such as angiotensin-converting enzyme (ACE) inhibition were investigated. The results found that the growth of B. longum was increased during 0–24 h, while viability declined after 24 h. The greatest concentrations of phenolic compounds and flavonoids were observed at 709.81 and 42.07 mg/mL, respectively. The antioxidant activity levels measured using the 2,2-diphenyl-1-picrylhydrazyl (DPPH•) and 2,2′ -azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS•+) assays were 42.65 % and 45.24 %, respectively. The biological activity, particularly ACE inhibition, was assessed in vitro and was correlated with blood pressure regulation. The fermented mushroom trimming extract had a maximum ACE inhibition value of 9.91 % and a half-maximal inhibitory concentration (IC50) value of 2,134.08 mg/L, making it more effective than the control group with an IC50 value of 2,482.36 mg/L.http://www.sciencedirect.com/science/article/pii/S2772502225000241Flammulina velutipesBifidobacterium longumPhytochemicalBioactive peptideACE inhibition |
| spellingShingle | Napassorn Peasura Pornrat Sinchaipanit Kanokwan Yodin A novel source of phytochemical and bioactive peptide from fermented mushroom trimming waste extract by Bifidobacterium longum Applied Food Research Flammulina velutipes Bifidobacterium longum Phytochemical Bioactive peptide ACE inhibition |
| title | A novel source of phytochemical and bioactive peptide from fermented mushroom trimming waste extract by Bifidobacterium longum |
| title_full | A novel source of phytochemical and bioactive peptide from fermented mushroom trimming waste extract by Bifidobacterium longum |
| title_fullStr | A novel source of phytochemical and bioactive peptide from fermented mushroom trimming waste extract by Bifidobacterium longum |
| title_full_unstemmed | A novel source of phytochemical and bioactive peptide from fermented mushroom trimming waste extract by Bifidobacterium longum |
| title_short | A novel source of phytochemical and bioactive peptide from fermented mushroom trimming waste extract by Bifidobacterium longum |
| title_sort | novel source of phytochemical and bioactive peptide from fermented mushroom trimming waste extract by bifidobacterium longum |
| topic | Flammulina velutipes Bifidobacterium longum Phytochemical Bioactive peptide ACE inhibition |
| url | http://www.sciencedirect.com/science/article/pii/S2772502225000241 |
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