Speech sound processing deficits and training-induced neural plasticity in rats with dyslexia gene knockdown.
In utero RNAi of the dyslexia-associated gene Kiaa0319 in rats (KIA-) degrades cortical responses to speech sounds and increases trial-by-trial variability in onset latency. We tested the hypothesis that KIA- rats would be impaired at speech sound discrimination. KIA- rats needed twice as much train...
Saved in:
| Main Authors: | Tracy M Centanni, Fuyi Chen, Anne M Booker, Crystal T Engineer, Andrew M Sloan, Robert L Rennaker, Joseph J LoTurco, Michael P Kilgard |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0098439 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Use of a predictor cue during a speech sound discrimination task in a Cntnap2 knockout rat model of autism.
by: Tracy M Centanni, et al.
Published: (2025-01-01) -
Social Understanding and Friendships in Children with Attention Deficit/Hyperactivity Disorder or Dyslexia
by: Sofia Kouvava, et al.
Published: (2025-02-01) -
Speech paired vagus nerve stimulation restores neural sound processing in a rat model of autism
by: Brendan M. Williams, et al.
Published: (2025-06-01) -
Attention deficit hyperactivity disorder and dyslexia: a history of overlap
by: Alexandra Prufer de Queiroz Campos Araujo
Published: (2012-02-01) -
Sound localization and word discrimination in reverberant environment in children with developmental dyslexia
by: Wendy Castro-Camacho, et al.
Published: (2015-04-01)