Recent Advances in Electrochemical Glycobiosensing
Biosensors based on electrochemical transduction mechanisms have recently made advances into the field of glycan analysis. These glyco-biosensors offer simple, rapid, sensitive, and economical approaches to the measurement need for rapid glycan analysis for biomarker detection, cancer and disease d...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | International Journal of Electrochemistry |
| Online Access: | http://dx.doi.org/10.4061/2011/825790 |
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| author | Germarie Sánchez-Pomales Rebecca A. Zangmeister |
| author_facet | Germarie Sánchez-Pomales Rebecca A. Zangmeister |
| author_sort | Germarie Sánchez-Pomales |
| collection | DOAJ |
| description | Biosensors based on electrochemical transduction mechanisms have recently made advances into the field of glycan analysis. These glyco-biosensors offer simple, rapid, sensitive, and economical approaches to the measurement need for rapid glycan analysis for biomarker detection, cancer and disease diagnostics, and bioprocess monitoring of therapeutic glycoproteins. Although the prevalent methods of glycan analysis (high-performance liquid chromatography, mass spectrometry, and nuclear magnetic resonance spectroscopy) provide detailed identification and structural analysis of glycan species, there are significantly few low-cost, rapid glycan assays available for diagnostic and screening applications. Here we review instances in which glyco-biosensors have been used for glycan analysis using a variety of electrochemical transduction mechanisms (e.g., amperometric, potentiometric, impedimetric, and voltammetric), selective binding agents (e.g., lectins and antibodies), and redox species (e.g., enzyme substrates, inorganic, and nanomaterial). |
| format | Article |
| id | doaj-art-bb6ab0a40cdc4d41add0323aecf23612 |
| institution | Kabale University |
| issn | 2090-3537 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Electrochemistry |
| spelling | doaj-art-bb6ab0a40cdc4d41add0323aecf236122025-02-03T05:51:48ZengWileyInternational Journal of Electrochemistry2090-35372011-01-01201110.4061/2011/825790825790Recent Advances in Electrochemical GlycobiosensingGermarie Sánchez-Pomales0Rebecca A. Zangmeister1Bioprocess Measurements Group, Biochemical Science Division, Material Measurement Laboratory, National Institute of Standards and Technology, 100 Bureau Drive, Gaithersburg, MD 20899, USABioprocess Measurements Group, Biochemical Science Division, Material Measurement Laboratory, National Institute of Standards and Technology, 100 Bureau Drive, Gaithersburg, MD 20899, USABiosensors based on electrochemical transduction mechanisms have recently made advances into the field of glycan analysis. These glyco-biosensors offer simple, rapid, sensitive, and economical approaches to the measurement need for rapid glycan analysis for biomarker detection, cancer and disease diagnostics, and bioprocess monitoring of therapeutic glycoproteins. Although the prevalent methods of glycan analysis (high-performance liquid chromatography, mass spectrometry, and nuclear magnetic resonance spectroscopy) provide detailed identification and structural analysis of glycan species, there are significantly few low-cost, rapid glycan assays available for diagnostic and screening applications. Here we review instances in which glyco-biosensors have been used for glycan analysis using a variety of electrochemical transduction mechanisms (e.g., amperometric, potentiometric, impedimetric, and voltammetric), selective binding agents (e.g., lectins and antibodies), and redox species (e.g., enzyme substrates, inorganic, and nanomaterial).http://dx.doi.org/10.4061/2011/825790 |
| spellingShingle | Germarie Sánchez-Pomales Rebecca A. Zangmeister Recent Advances in Electrochemical Glycobiosensing International Journal of Electrochemistry |
| title | Recent Advances in Electrochemical Glycobiosensing |
| title_full | Recent Advances in Electrochemical Glycobiosensing |
| title_fullStr | Recent Advances in Electrochemical Glycobiosensing |
| title_full_unstemmed | Recent Advances in Electrochemical Glycobiosensing |
| title_short | Recent Advances in Electrochemical Glycobiosensing |
| title_sort | recent advances in electrochemical glycobiosensing |
| url | http://dx.doi.org/10.4061/2011/825790 |
| work_keys_str_mv | AT germariesanchezpomales recentadvancesinelectrochemicalglycobiosensing AT rebeccaazangmeister recentadvancesinelectrochemicalglycobiosensing |