The role of temozolomide as adjuvant therapy in glioblastoma management: a systematic review and meta-analysis.

The role of temozolomide as adjuvant therapy in glioblastoma management: a systematic review and meta-analysis.

Abstract Introduction The persistent challenge of temozolomide (TMZ) resistance and the eventual recurrence of tumors underscore the need for ongoing research and the development of novel therapeutic strategies. We aim to consolidate existing evidence related to the safety and efficacy of TMZ as adj...

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Main Authors: Made Agus Mahendra Inggas, Utsav Patel, Jeremiah Hilkiah Wijaya, Nina Otinashvili, Vyshnav Rajagopal Menon, Abhay Krishnan Iyer, Tawfiq Turjman, Surbhi Dadwal, Mari Gadaevi, Azada Ismayilova, Shiva Jashwanth Gaddam, Prakriti Arya, Nihar Upadhyay, Saurabh Kataria
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Cancer
Subjects:
Glioblastoma
Overall survival
Progression free survival
Temozolomide.
Online Access:https://doi.org/10.1186/s12885-025-13757-1
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