COMPLICATIONS AFTER HEPATECTOMY

ABSTRACT Complete removal of metastatic disease and maintenance of an adequate liver remnant remains the only treatment option with curative intent concerning colorectal liver metastases. Surgery impacts on the long-term prognosis and complications adversely affect oncological results. The actual mo...

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Main Authors: Claudemiro Quireze Junior, Fabricio Ferreira Coelho, Agnaldo Soares Lima, Hugo Pinto Marques, Martin Palavecino, Timothy Pawlik, Rene Adam, Olivier Soubrane, Paulo Herman, Ricardo Lemos Cotta-Pereira
Format: Article
Language:English
Published: Colégio Brasileiro de Cirurgia Digestiva 2025-01-01
Series:ABCD: Arquivos Brasileiros de Cirurgia Digestiva
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202024000100507&lng=en&tlng=en
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author Claudemiro Quireze Junior
Fabricio Ferreira Coelho
Agnaldo Soares Lima
Hugo Pinto Marques
Martin Palavecino
Timothy Pawlik
Rene Adam
Olivier Soubrane
Paulo Herman
Ricardo Lemos Cotta-Pereira
author_facet Claudemiro Quireze Junior
Fabricio Ferreira Coelho
Agnaldo Soares Lima
Hugo Pinto Marques
Martin Palavecino
Timothy Pawlik
Rene Adam
Olivier Soubrane
Paulo Herman
Ricardo Lemos Cotta-Pereira
author_sort Claudemiro Quireze Junior
collection DOAJ
description ABSTRACT Complete removal of metastatic disease and maintenance of an adequate liver remnant remains the only treatment option with curative intent concerning colorectal liver metastases. Surgery impacts on the long-term prognosis and complications adversely affect oncological results. The actual morbidity involving this scenario is debatable and estimated to be ranging from 15% to 50%. Postoperative complications eventually lead to an increase in both mortality rates and tumor recurrence. Biliary fistula and liver failure are the leading complications following liver resection to metastatic colorectal cancer. Prophylactic drainage does not prevent fistulas or hemorrhage. Drainage along with endoscopic intervention and/or surgery may be necessary for grade B and C fistulas. Liver failure is a potentially lethal complication with few therapeutic options. Patient selection and preoperative care are crucial for its prevention.
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institution Kabale University
issn 0102-6720
language English
publishDate 2025-01-01
publisher Colégio Brasileiro de Cirurgia Digestiva
record_format Article
series ABCD: Arquivos Brasileiros de Cirurgia Digestiva
spelling doaj-art-bb2fa38dbfb046959989fcc385dd0fbd2025-01-21T07:44:09ZengColégio Brasileiro de Cirurgia DigestivaABCD: Arquivos Brasileiros de Cirurgia Digestiva0102-67202025-01-013710.1590/0102-6720202400062e1856COMPLICATIONS AFTER HEPATECTOMYClaudemiro Quireze Juniorhttps://orcid.org/0000-0002-5569-5052Fabricio Ferreira Coelhohttps://orcid.org/0000-0002-5290-8286Agnaldo Soares Limahttps://orcid.org/0000-0001-6421-3062Hugo Pinto Marqueshttps://orcid.org/0000-0003-3540-0488Martin Palavecinohttps://orcid.org/0000-0002-5152-0159Timothy Pawlikhttps://orcid.org/0000-0002-7994-9870Rene Adamhttps://orcid.org/0000-0003-2169-5449Olivier Soubranehttps://orcid.org/0000-0002-2059-1237Paulo Hermanhttps://orcid.org/0000-0003-2859-5846Ricardo Lemos Cotta-Pereirahttps://orcid.org/0009-0006-0755-0883ABSTRACT Complete removal of metastatic disease and maintenance of an adequate liver remnant remains the only treatment option with curative intent concerning colorectal liver metastases. Surgery impacts on the long-term prognosis and complications adversely affect oncological results. The actual morbidity involving this scenario is debatable and estimated to be ranging from 15% to 50%. Postoperative complications eventually lead to an increase in both mortality rates and tumor recurrence. Biliary fistula and liver failure are the leading complications following liver resection to metastatic colorectal cancer. Prophylactic drainage does not prevent fistulas or hemorrhage. Drainage along with endoscopic intervention and/or surgery may be necessary for grade B and C fistulas. Liver failure is a potentially lethal complication with few therapeutic options. Patient selection and preoperative care are crucial for its prevention.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202024000100507&lng=en&tlng=enNeoplasm metastasisHepatectomyBiliary fistulaLiver failureHemorrhageColorectal neoplasms
spellingShingle Claudemiro Quireze Junior
Fabricio Ferreira Coelho
Agnaldo Soares Lima
Hugo Pinto Marques
Martin Palavecino
Timothy Pawlik
Rene Adam
Olivier Soubrane
Paulo Herman
Ricardo Lemos Cotta-Pereira
COMPLICATIONS AFTER HEPATECTOMY
ABCD: Arquivos Brasileiros de Cirurgia Digestiva
Neoplasm metastasis
Hepatectomy
Biliary fistula
Liver failure
Hemorrhage
Colorectal neoplasms
title COMPLICATIONS AFTER HEPATECTOMY
title_full COMPLICATIONS AFTER HEPATECTOMY
title_fullStr COMPLICATIONS AFTER HEPATECTOMY
title_full_unstemmed COMPLICATIONS AFTER HEPATECTOMY
title_short COMPLICATIONS AFTER HEPATECTOMY
title_sort complications after hepatectomy
topic Neoplasm metastasis
Hepatectomy
Biliary fistula
Liver failure
Hemorrhage
Colorectal neoplasms
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202024000100507&lng=en&tlng=en
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AT fabricioferreiracoelho complicationsafterhepatectomy
AT agnaldosoareslima complicationsafterhepatectomy
AT hugopintomarques complicationsafterhepatectomy
AT martinpalavecino complicationsafterhepatectomy
AT timothypawlik complicationsafterhepatectomy
AT reneadam complicationsafterhepatectomy
AT oliviersoubrane complicationsafterhepatectomy
AT pauloherman complicationsafterhepatectomy
AT ricardolemoscottapereira complicationsafterhepatectomy