Photocatalytic Inactivation Effect of Gold-Doped TiO2 (Au/TiO2) Nanocomposites on Human Colon Carcinoma LoVo Cells
The photocatalytic inactivation effecting of gold-doped TiO2 (Au/TiO2) nanocomposites on human colon carcinoma LoVo cells was investigated for the first time. The Au/TiO2 samples containing different amounts of Au (1–4 wt%) were prepared by deposition-precipitation (DP) method. These synthesized Au/...
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| Format: | Article |
| Language: | English |
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Wiley
2007-01-01
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| Series: | International Journal of Photoenergy |
| Online Access: | http://dx.doi.org/10.1155/2007/97308 |
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| author | Juan Xu Yi Sun Yaomin Zhao Junjie Huang Chunmei Chen Zhiyu Jiang |
| author_facet | Juan Xu Yi Sun Yaomin Zhao Junjie Huang Chunmei Chen Zhiyu Jiang |
| author_sort | Juan Xu |
| collection | DOAJ |
| description | The photocatalytic inactivation effecting of gold-doped TiO2 (Au/TiO2) nanocomposites on human colon carcinoma LoVo cells was investigated for the first time. The Au/TiO2 samples containing different amounts of Au (1–4 wt%) were prepared by deposition-precipitation (DP) method. These synthesized Au/TiO2 nanocomposites were characterized by transmission electron microscopy (TEM) and inductively coupled plasma atomic emission spectroscopy. It was found that the photocatalytic inactivation effect of TiO2 nanoparticles on LoVo cancer cells could be greatly improved by the surface modification of Au nanoparticles. Furthermore, the loading amount of Au on the surface of TiO2 nanoparticles affects the photocatalytic inactivation efficiency strongly, and it was found that the most efficient nanocomposites were TiO2 nanoparticles doped with 2 wt% Au. When 50 μg/mL 2 wt% Au/TiO2 nanocomposites were used, all of the LoVo cancer cells were killed under the irradiation of UV light (λmax = 365 nm, Intensity = 1.8 mW/cm2) within 100 minutes. But for 50 μg/mL TiO2 nanoparticles, only 40% cancer cells were killed under the same condition. |
| format | Article |
| id | doaj-art-bb23fb28fd37450f85f167ad63a631f5 |
| institution | Kabale University |
| issn | 1110-662X 1687-529X |
| language | English |
| publishDate | 2007-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Photoenergy |
| spelling | doaj-art-bb23fb28fd37450f85f167ad63a631f52025-02-03T06:08:29ZengWileyInternational Journal of Photoenergy1110-662X1687-529X2007-01-01200710.1155/2007/9730897308Photocatalytic Inactivation Effect of Gold-Doped TiO2 (Au/TiO2) Nanocomposites on Human Colon Carcinoma LoVo CellsJuan Xu0Yi Sun1Yaomin Zhao2Junjie Huang3Chunmei Chen4Zhiyu Jiang5Department of Chemical Engineering, Jiangsu Polytechnic University, Changzhou 213164, ChinaDepartment of Chemistry, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Fudan University, Shanghai 200433, ChinaDepartment of Chemistry, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Fudan University, Shanghai 200433, ChinaDepartment of Chemistry, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Fudan University, Shanghai 200433, ChinaInstitute of Genetics School of Life Sciences, Fudan University, Shanghai 200433, ChinaDepartment of Chemistry, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Fudan University, Shanghai 200433, ChinaThe photocatalytic inactivation effecting of gold-doped TiO2 (Au/TiO2) nanocomposites on human colon carcinoma LoVo cells was investigated for the first time. The Au/TiO2 samples containing different amounts of Au (1–4 wt%) were prepared by deposition-precipitation (DP) method. These synthesized Au/TiO2 nanocomposites were characterized by transmission electron microscopy (TEM) and inductively coupled plasma atomic emission spectroscopy. It was found that the photocatalytic inactivation effect of TiO2 nanoparticles on LoVo cancer cells could be greatly improved by the surface modification of Au nanoparticles. Furthermore, the loading amount of Au on the surface of TiO2 nanoparticles affects the photocatalytic inactivation efficiency strongly, and it was found that the most efficient nanocomposites were TiO2 nanoparticles doped with 2 wt% Au. When 50 μg/mL 2 wt% Au/TiO2 nanocomposites were used, all of the LoVo cancer cells were killed under the irradiation of UV light (λmax = 365 nm, Intensity = 1.8 mW/cm2) within 100 minutes. But for 50 μg/mL TiO2 nanoparticles, only 40% cancer cells were killed under the same condition.http://dx.doi.org/10.1155/2007/97308 |
| spellingShingle | Juan Xu Yi Sun Yaomin Zhao Junjie Huang Chunmei Chen Zhiyu Jiang Photocatalytic Inactivation Effect of Gold-Doped TiO2 (Au/TiO2) Nanocomposites on Human Colon Carcinoma LoVo Cells International Journal of Photoenergy |
| title | Photocatalytic Inactivation Effect of Gold-Doped TiO2 (Au/TiO2) Nanocomposites on Human Colon Carcinoma LoVo Cells |
| title_full | Photocatalytic Inactivation Effect of Gold-Doped TiO2 (Au/TiO2) Nanocomposites on Human Colon Carcinoma LoVo Cells |
| title_fullStr | Photocatalytic Inactivation Effect of Gold-Doped TiO2 (Au/TiO2) Nanocomposites on Human Colon Carcinoma LoVo Cells |
| title_full_unstemmed | Photocatalytic Inactivation Effect of Gold-Doped TiO2 (Au/TiO2) Nanocomposites on Human Colon Carcinoma LoVo Cells |
| title_short | Photocatalytic Inactivation Effect of Gold-Doped TiO2 (Au/TiO2) Nanocomposites on Human Colon Carcinoma LoVo Cells |
| title_sort | photocatalytic inactivation effect of gold doped tio2 au tio2 nanocomposites on human colon carcinoma lovo cells |
| url | http://dx.doi.org/10.1155/2007/97308 |
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