Transcriptional landscape and chromatin accessibility reveal key regulators for liver regenerative initiation and organoid formation

Summary: Liver regeneration is a well-organized and phase-restricted process that involves chromatin remodeling and transcriptional alterations. However, the specific transcription factors (TFs) that act as key “switches” to initiate hepatocyte regeneration and organoid formation remain unclear. Com...

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Bibliographic Details
Main Authors: Jiabei Lian, Yachun An, Wenjing Wei, Yao Lu, Xiyu Zhang, Gongping Sun, Haiyang Guo, Longjin Xu, Xuena Chen, Huili Hu
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725004048
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