Interruption of intermittent hypoxia attenuates the severity of pulmonary fibrosis in male mice

Interruption of intermittent hypoxia attenuates the severity of pulmonary fibrosis in male mice

Abstract Obstructive sleep apnoea (OSA) leading to chronic intermittent hypoxia (CIH) is a common comorbidity associated with idiopathic pulmonary fibrosis (IPF), a progressive fatal disease characterized by adverse lung remodeling and parenchymal stiffening. In the mouse model of lung fibrosis indu...

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Bibliographic Details
Main Authors: Zakaria Maakoul, Celine‐Hivda Yegen, Dominique Marchant, Jean‐Francois Bernaudin, Carole Planès, Nicolas Voituron, Emilie Boncoeur
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Physiological Reports
Subjects:
intermittent hypoxia
lung damages
macrophages
obstructive sleep apnoea
pulmonary fibrosis
Online Access:https://doi.org/10.14814/phy2.70335
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