Intrinsic Dissolution Modeling: Interdependence Between Dissolution Rate, Solubility, and Boundary Layer Thickness

Intrinsic Dissolution Modeling: Interdependence Between Dissolution Rate, Solubility, and Boundary Layer Thickness

<b>Background/Objectives</b>: In the past, many drug release models have been presented which attempt to describe the interaction of drugs and excipients in a formulation. Nevertheless, modeling the intrinsic dissolution behavior is essential for understanding the fundamental dissolution...

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Bibliographic Details
Main Authors: Amelie Marie Mattusch, Gerhard Schaldach, Jens Bartsch, Markus Thommes
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Pharmaceutics
Subjects:
dissolution rate
solubility
Reynolds number
hydrodynamics
boundary layer
flow channel
Online Access:https://www.mdpi.com/1999-4923/17/5/570
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