Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab
The pathogenesis of mastocytosis is not well defined and thus treatment remains challenging and remains on a palliative basis. We present two cases (a 48-year-old woman and a 57-year-old man) with indolent systemic mastocytosis in whom omalizumab (anti-IgE) reduced gastrointestinal and cutaneous sym...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/903541 |
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| _version_ | 1832551001853263872 |
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| author | Sofie Lieberoth Simon Francis Thomsen |
| author_facet | Sofie Lieberoth Simon Francis Thomsen |
| author_sort | Sofie Lieberoth |
| collection | DOAJ |
| description | The pathogenesis of mastocytosis is not well defined and thus treatment remains challenging and remains on a palliative basis. We present two cases (a 48-year-old woman and a 57-year-old man) with indolent systemic mastocytosis in whom omalizumab (anti-IgE) reduced gastrointestinal and cutaneous symptoms significantly. This observation provides additional insight into the effects of omalizumab on systemic mastocytosis. |
| format | Article |
| id | doaj-art-bad30662494c429d83df461ea1c4e2ae |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-bad30662494c429d83df461ea1c4e2ae2025-02-03T06:05:20ZengWileyCase Reports in Medicine1687-96271687-96352015-01-01201510.1155/2015/903541903541Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with OmalizumabSofie Lieberoth0Simon Francis Thomsen1Department of Dermatology, Bispebjerg Hospital, 2400 Copenhagen NV, DenmarkDepartment of Dermatology, Bispebjerg Hospital, 2400 Copenhagen NV, DenmarkThe pathogenesis of mastocytosis is not well defined and thus treatment remains challenging and remains on a palliative basis. We present two cases (a 48-year-old woman and a 57-year-old man) with indolent systemic mastocytosis in whom omalizumab (anti-IgE) reduced gastrointestinal and cutaneous symptoms significantly. This observation provides additional insight into the effects of omalizumab on systemic mastocytosis.http://dx.doi.org/10.1155/2015/903541 |
| spellingShingle | Sofie Lieberoth Simon Francis Thomsen Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab Case Reports in Medicine |
| title | Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab |
| title_full | Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab |
| title_fullStr | Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab |
| title_full_unstemmed | Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab |
| title_short | Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab |
| title_sort | cutaneous and gastrointestinal symptoms in two patients with systemic mastocytosis successfully treated with omalizumab |
| url | http://dx.doi.org/10.1155/2015/903541 |
| work_keys_str_mv | AT sofielieberoth cutaneousandgastrointestinalsymptomsintwopatientswithsystemicmastocytosissuccessfullytreatedwithomalizumab AT simonfrancisthomsen cutaneousandgastrointestinalsymptomsintwopatientswithsystemicmastocytosissuccessfullytreatedwithomalizumab |