PDMS SlipChip: Optimizing Sealing, Slipping, and Biocompatibility Using Low-Viscosity Silicone Oils

PDMS SlipChip: Optimizing Sealing, Slipping, and Biocompatibility Using Low-Viscosity Silicone Oils

The Polydimethylsiloxane (PDMS) SlipChip is a microfluidic platform enabling fluid manipulation without pumps or valves, simplifying operation and reducing reagent use. High-viscosity silicone oils (e.g., 5000–10,000 cSt) improve sealing but frequently block microfluidic channels, reducing usability...

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Bibliographic Details
Main Authors: Rafia Inaam, Marcela F. Bolontrade, Shunya Okamoto, Takayuki Shibata, Tuhin Subhra Santra, Moeto Nagai
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Micromachines
Subjects:
PDMS SlipChip
sealing performance
curing temperature
silicone oil lubrication
concentration gradients
biocompatibility
Online Access:https://www.mdpi.com/2072-666X/16/5/525
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