A pH/MMP-9 smart dual-responsive liposome GBE@LP co-delivers and controls the release of GB1107/BMS1166/Enzalutamide for liver cancer immunotherapy

A pH/MMP-9 smart dual-responsive liposome GBE@LP co-delivers and controls the release of GB1107/BMS1166/Enzalutamide for liver cancer immunotherapy

Liver cancer is one of the malignant tumors with high morbidity and mortality worldwide and lacks effective clinical treatments. CD8+ T cell-based immunotherapy is the most promising option for the treatment of liver cancer, but its application is severely limited by low infiltration and functional...

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Bibliographic Details
Main Authors: Shijia Lu, Chenxiao Zhang, Huiru Wu, Junjie Wang, Jinglong Wang, Limei Zhao, Tianyang Ren, Guofei Li
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Materials Today Bio
Subjects:
Liver cancer
Cancer immunotherapy
Liposome drug delivery system
Intelligent material
Combination therapy
ICB
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425003618
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